Search Results - "Özmen, Ümmühan"

Biological Effects and Crystal X‐Ray Study of Novel Schiff Base Containing Pentafluorophenyl Hydrazine: In Vitro and in Silico Studies by Hamurcu, Fatma, Özmen, Ümmühan Özdemir, Şentürk, Ozan Sanlı, Kaya, Kerem, Adem, Sevki, Erden, Büşra Aksoy, Celebioglu, Hasan Ufuk, Erden, Yavuz, Taslimi, Parham

“…A novel Schiff base namely 3,5‐di‐tert‐butyl‐6‐((2‐(perfluorophenyl)hydrazono)methyl)phenol was successfully synthesized and characterized using FT‐IR and…”
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Screening of novel chemical compounds as possible inhibitors of carbonic anhydrase and photosynthetic activity of photosystem II by Karacan, Mehmet Sayım, Zharmukhamedov, Sergei K, Mamaş, Serhat, Kupriyanova, Elena V, Shitov, Alexandr V, Klimov, Vyacheslav V, Özbek, Neslihan, Özmen, Ümmühan, Gündüzalp, Ayla, Schmitt, Franz-Josef, Karacan, Nurcan, Friedrich, Thomas, Los, Dmitry A, Carpentier, Robert, Allakhverdiev, Suleyman I

“…Thirty novel chemical compounds were designed and synthesized expecting that they would be possible inhibitors. From this number eleven were organic bases,…”
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New aromatic/heteroaromatic propanesulfonylhydrazone compounds: Synthesis, physical properties and inhibition studies against carbonic anhydrase II (CAII) enzyme by Özmen Özdemir, Ümmühan, Altuntaş, Ayşegül, Gündüzalp, Ayla Balaban, Arslan, Fatma, Hamurcu, Fatma

“…[Display omitted] •Sulfonylhydrazones were characterized.•Enzyme activity was evaluated.•SAR was investigated. Some new aromatic/heteroaromatic…”
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New sulfonylhydrazones containing methane sulfonic acid hydrazıde havıng human anticarbonic anhydrase and antimicrobıal activıty: synthesis, spectroscopic characterization, electrochemical properties, and biological activıties by Uzun, Demet, Erdoğdu, Ebru, Balaban Gündüzalp, Ayla, Özmen Özdemir, Ümmühan, Öztürk, Ali, Özbek, Neslihan, Kaya, Kerem, Abdulmajet, Olkar

“…In this work, new sulfonylhydrazones nomenclatured as 3,5-ditertbutylsalicylaldehyde methane­sulfonylhydrazone (II), 3-tertbutylsalicylaldehyde…”
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Synthesis, characterization, molecular docking and in vitro screening of new metal complexes with coumarin Schiff base as anticholine esterase and antipancreatic cholesterol esterase agents by Şahin, Ömer, Özmen Özdemir, Ümmühan, Seferoğlu, Nurgül, Adem, Şevki, Seferoğlu, Zeynel

“…In this work, Combining coumarin and thiazole with 3-tertiary butyl salicylaldehyde into in a single molecule, new Schiff base (CTS), and its metal complexes…”
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Bioactive sulfonyl hydrazones with alkyl derivative: Characterization, ADME properties, molecular docking studies and investigation of inhibition on choline esterase enzymes for the diagnosis of Alzheimer's disease by Bilen, Esra, Özdemir Özmen, Ümmühan, Çete, Servet, Alyar, Saliha, Yaşar, Ahmet

“…In this work, new sulfonylhydrazone compounds with alkyl derivatives (SH1– SH4 series) were synthesized via a green chemistry method, and their inhibition…”
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Synthesis, spectroscopic characterizations, carbonic anhydrase II inhibitory activity, anticancer activity and docking studies of new Schiff bases of sulfa drugs by Alyar, Saliha, Özmen, Ümmühan Özdemir, Adem, Şevki, Alyar, Hamit, Bilen, Esra, Kaya, Kerem

“…•New Schiff bases of sulfa drugs and their Pd(II) and Cu(II) complexes were synthesized.•Inhibitory activity of these compounds were evaluated against hCA II…”
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Eco-friendly and potential colin esterase enzyme inhibitor agent sulfonyl hydrazone series: Synthesis, Bioactivity Screening, DFT, ADME properties, and Molecular Docking study by Ozdemir Ozmen, Ummuhan, Tuzun, Burak, Ayan, Esra Bilen, Cevrimli, Bekir Sıtkı

“…•A new eco-friendly the sulfonylhydrazone compounds were synthesized.•Anti-cholinesterase activity of sulfonylhydrazone compounds were evaluated.•DFT…”
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Biochemical properties of Schiff bases derived from FDA-approved sulfa drugs: Synthesis, ADME/molecular docking studies, and anticancer activity by Alyar, Saliha, Alyar, Hamit, Özdemir Özmen, Ümmühan, Aktaş, Okan, Erdem, Kelime

“…•Four (L1-L4) new sulfa Schiff bases were synthesized and characterized.•The synthesized compounds were screened for their anticancer activity against the…”
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Cytotoxic effects, carbonic anhydrase isoenzymes, α-glycosidase and acetylcholinesterase inhibitory properties, and molecular docking studies of heteroatom-containing sulfonyl hydrazone derivatives by Celebioglu, Hasan Ufuk, Erden, Yavuz, Hamurcu, Fatma, Taslimi, Parham, Şentürk, Ozan Sanlı, Özmen, Ümmühan Özdemir, Tuzun, Burak, Gulçin, İlhami

“…Today, interest in studies on the search for new drugs to be used in diseases such as cancer, cardiovascular diseases, neurodegenerative diseases and diabetes,…”
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Synthesis, spectroscopic characterizations, enzyme inhibition, molecular docking study and DFT calculations of new Schiff bases of sulfa drugs by Alyar, Saliha, Şen, Tülin, Özmen, Ümmühan Özdemir, Alyar, Hamit, Adem, Şevki, Şen, Cihan

“…New Schiff bases were synthesized (Z)-4-((4-(diethylamino)benzylidene)amino)-N-(3,4-dimethylisoxazol-5-yl)benzenesulfonamide (L1) and…”
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A highly selective and sensitive chemosensor derived coumarin–thiazole for colorimetric and fluorimetric detection of CN− ion in DMSO and aqueous solution: synthesis, sensing ability, Pd(II)/Pt(II) complexes and theoretical studies by Şahin, Ömer, Özdemir, Ümmühan Özmen, Seferoğlu, Nurgül, Aydıner, Burcu, Sarı, Musa, Tunç, Tuncay, Seferoğlu, Zeynel

“…A colorimetric and fluorescence turn-on cyanide probe, including coumarin–thiazole and imine (azomethine) group, has been designed and synthesized. It showed…”
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New platinum (II) and palladium (II) complexes of coumarin-thiazole Schiff base with a fluorescent chemosensor properties: Synthesis, spectroscopic characterization, X-ray structure determination, in vitro anticancer activity on various human carcinoma cell lines and computational studies by Şahin, Ömer, Özdemir, Ümmühan Özmen, Seferoğlu, Nurgül, Genc, Zuhal Karagöz, Kaya, Kerem, Aydıner, Burcu, Tekin, Suat, Seferoğlu, Zeynel

“…A new coumarin-thiazole based Schiff base (Ligand, L) and its Pd(II), Pt(II) complexes; ([Pd(L)2] and [Pt(L)2]), were synthesized and characterized using…”
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Biological evaluation of Schiff bases containing dopamine as antibacterial /antifungal and potential Anti COVID-19 agents: Design, synthesis, characterization, molecular docking studies, and ADME properties by Ünlü, Ayse, Özmen, Ümmühan Özdemir, Alyar, Saliha, Öztürk, Ali, Alyar, Hamit, Gündüzalp, Ayla Balaban

“…•A new dopamine Schiff bases were synthesized as antimicrobial and potential Anti COVID-19 agents:•The antimicrobial properties of the synthesized dopamine…”
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Sulfonyl hydrazone derivatives containing acetonaphtone as anticholinesterase inhibitors for the treatment of Alzheimer's: X-ray single-crystal analysis, and multifaced theoretical calculations by Özdemir Özmen, Ümmühan, Alyar, Saliha, Bilen Ayan, Esra, Canbolat, Nüveyre, Hamurcu, Fatma, Alyar, Hamit, Muhammet, Sinan Mithat, Kaya, Kerem

“…•2-Hydroxy-1-acetonaphthone-ethanesulfonylhydrazone was investigated by X-ray diffraction.•Anti-cholinesterase activity of sulfonylhydrazone compounds were…”
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Sulfonamide-derived hydrazone compounds and their Pd (II) complexes: Synthesis, spectroscopic characterization, X-ray structure determination, in vitro antibacterial activity and computational studies by Özbek, Neslihan, Özdemir, Ümmühan Özmen, Altun, Ahmet Fazıl, Şahin, Ertan

“…A new sulfonamide-derived prophane sulfonyl hydrazone compounds: 2-hydroxy- acetophenoneprophanesulfonylhydrazone (afpsh), 5-Cl-2-hydroxyacetophenoneprophane…”
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Structural, physicochemical characterization, theoretical studies of carboxamides and their Cu(II), Zn(II) complexes having antibacterial activities against E. coli by Aktan, Ebru, Gündüzalp, Ayla Balaban, Özmen, Ümmühan Özdemir

“…The carboxamides; N,N′-bis(thiophene-2-carboxamido)-1,3-diaminopropanol (L1) and N,N′-bis(furan-2-carboxamido)-1,3-diaminopropanol (L2) were synthesized and…”
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Copper(II) sulfonamide complexes having enzyme inhibition activities on carbonic anhydrase I: synthesis, characterization and inhibition studies by Uzun, Demet, Balaban Gündüzalp, Ayla, Parlakgümüş, Gökhan, Özmen, Ümmühan Özdemir, Özbek, Neslihan, Aktan, Ebru

“…In our present study, copper(II) sulfonamide complexes titled as bis-(2 acetylfuranmethanesulfonylhydrazone) copper(II) chloride,…”
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Synthesis, characterization and antibacterial activity of new sulfonyl hydrazone derivatives and their nickel(II) complexes by Özmen, Ümmühan Özdemir, Olgun, Gülçin

“…Prophane sulfonic acid hydrazide (psh: CH 3CH 2CH 2SO 2NHNH 2) derivatives as salicylaldehydeprophanesulfonylhydrazone (salpsh),…”
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Synthesis, characterization, antibacterial activities and carbonic anhydrase enzyme inhibitor effects of new arylsulfonylhydrazone and their Ni(II), Co(II) complexes by Özdemir, Ümmühan Özmen, Arslan, Fatma, Hamurcu, Fatma

“…Ethane sulfonic acide hydrazide ( esh: CH 3CH 2SO 2NHNH 2) derivatives as 5-methylsalicyl-aldehydeethanesulfonylhydrazone ( 5msalesh),…”
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