Search Results - "Özenver, Nadire"
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Phytochemical inhibitors of the NLRP3 inflammasome for the treatment of inflammatory diseases
Published in Pharmacological research (01-08-2021)“…The NLRP3 inflammasome holds a crucial role in innate immune responses. Pathogen- and danger-associated molecular patterns may initiate inflammasome activation…”
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Identification of Prognostic and Predictive Biomarkers and Druggable Targets among 205 Antioxidant Genes in 21 Different Tumor Types via Data-Mining
Published in Pharmaceutics (28-01-2023)“…(1) Background: Oxidative stress is crucial in carcinogenesis and the response of tumors to treatment. Antioxidant genes are important determinants of…”
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Ethnopharmacology, phytochemistry, chemical ecology and invasion biology of Acanthus mollis L
Published in Journal of ethnopharmacology (01-03-2022)“…Acanthus mollis L. (Bear's Breeches) is a wide-spread medicinal and ornamental plant and is particularly suited to exemplarily illustrate the diverse aspects…”
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Identification and characterization of deschloro-chlorothricin obtained from a large natural product library targeting aurora A kinase in multiple myeloma
Published in Investigational new drugs (01-04-2021)“…Summary Multiple myeloma (MM) is a devastating disease with low survival rates worldwide. The mean lifetime of patients may be extendable with new drug…”
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Chemometric and Transcriptomic Profiling, Microtubule Disruption and Cell Death Induction by Secalonic Acid in Tumor Cells
Published in Molecules (Basel, Switzerland) (15-07-2020)“…Nature is an indispensable source of new drugs, providing unique bioactive lead structures for drug discovery. In the present study, secalonic acid F (SAF), a…”
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Kinome-Wide Profiling Identifies Human WNK3 as a Target of Cajanin Stilbene Acid from Cajanus cajan (L.) Millsp
Published in International journal of molecular sciences (28-01-2022)“…Pigeon Pea ( (L.) Millsp.) is a common food crop used in many parts of the world for nutritional purposes. One of its chemical constituents is cajanin stilbene…”
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Biginelli dihydropyrimidines carrying azole rings: Synthesis, computational studies, and evaluation of alpha‐glucosidase inhibitory and antimicrobial activities
Published in Journal of molecular structure (15-06-2024)“…•Various azole rings were linked to the core scaffold of Biginelli dihydropyrimidines (DHPMs).•DHPM-azole hybrids were tested for their α-glucosidase…”
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Structure-activity relationship of anticancer drug candidate quinones
Published in Turkish journal of chemistry (01-01-2024)“…Breast cancer is one of the most prevalent cancer types worldwide. Chemotherapy is a substantial approach in the management of breast cancer despite the…”
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Aloe-emodin as drug candidate for cancer therapy
Published in Oncotarget (03-04-2018)Get full text
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Immunotoxicity of Therapeutic Antibodies and Nanoparticles
Published in Critical reviews in immunology (2020)“…Therapeutic antibodies and nanotherapeutic drugs are of great concern due to their widespread use against numerous diseases worldwide. They are frequently used…”
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Cancer combination therapy with carnosic acid
Published in Biocell (2022)Get full text
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Molecular Modes of Action of an Aqueous Nerium oleander Extract in Cancer Cells In Vitro and In Vivo
Published in Molecules (Basel, Switzerland) (16-02-2023)“…Cancer drug resistance remains a major obstacle in clinical oncology. As most anticancer drugs are of natural origin, we investigated the anticancer potential…”
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Critical Reviews in Immunology
Published in Critical reviews in immunology (2020)“…Therapeutic antibodies and nanotherapeutic drugs are of great concern due to their widespread use against numerous diseases worldwide. They are frequently used…”
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Small molecule inhibitors and stimulators of inducible nitric oxide synthase in cancer cells from natural origin (phytochemicals, marine compounds, antibiotics)
Published in Biochemical pharmacology (01-06-2020)“…[Display omitted] Nitric oxide synthases (NOS) are a family of isoforms, which generate nitric oxide (NO). NO is one of the smallest molecules in nature and…”
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Cannabidiol (CBD) for relief from pain, anxiety, and epilepsy: A review
Published in International Journal of Applied Science and Engineering (01-12-2022)“…Cannabis or marijuana (Cannabis sativa) contains more than one hundred chemical compounds. Of these, tetrahydrocannabinol (THC) and cannabidiol (CBD) are the…”
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Cannabidiol (CBD) for relief from pain, anxiety, and epilepsy: A review
Published in International Journal of Applied Science and Engineering (2022)Get full text
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Activity of Cordycepin From Cordyceps sinensis Against Drug-Resistant Tumor Cells as Determined by Gene Expression and Drug Sensitivity Profiling
Published in Natural product communications (01-02-2021)“…Cordycepin is one of the substantial components of the parasitic fungus Cordyceps sinensis as well as other Cordyceps species. It exerts various effects such…”
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Molecular Modes of Action of an Aqueous INerium oleander/I Extract in Cancer Cells In Vitro and In Vivo
Published in Molecules (Basel, Switzerland) (01-02-2023)“…Cancer drug resistance remains a major obstacle in clinical oncology. As most anticancer drugs are of natural origin, we investigated the anticancer potential…”
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Molecular docking and ex vivo and in vitro anticholinesterase activity studies of Salvia sp. and highlighted rosmarinic acid
Published in Turkish journal of medical sciences (2015)“…To evaluate acetylcholinesterase (AChE) inhibitory activity and antioxidant capacity of the major molecule from Salvia sp., rosmarinic acid, as a drug…”
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