Search Results - "Özakpinar, Özlem Bingol"
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The Novel Function of Nesfatin-1 as an Anti-inflammatory and Antiapoptotic Peptide in Subarachnoid Hemorrhage–Induced Oxidative Brain Damage in Rats
Published in Neurosurgery (01-06-2011)“…Abstract BACKGROUND: There is substantial evidence to suggest that oxidative stress plays a significant role in the development of acute brain injury after…”
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Synthesis and anticancer activity of novel hydrazone linkage-based aryl sulfonate derivatives as apoptosis inducers
Published in Medicinal chemistry research (01-02-2022)“…In the present study, the various 28 hybrid molecules containing hydrazone and sulfonate moieties were synthesized and characterized by FTIR, 1 H-NMR, 13 C-NMR…”
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Synthesis and antiproliferative evaluation of novel 2-(4H-1,2,4-triazole-3-ylthio)acetamide derivatives as inducers of apoptosis in cancer cells
Published in European journal of medicinal chemistry (04-10-2016)“…In this study, a series of thiosemicarbazide derivatives 12–14, 1,2,4-triazol-3-thione derivatives 15–17 and compounds bearing…”
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Applying quality by design approach for the determination of potent paclitaxel loaded poly(lactic acid) based implants for localized tumor drug delivery
Published in International journal of polymeric materials (13-08-2023)“…In the present study, poly(lactic acid) (PLA) and poly(ethylene succinate) (PESu) or poly(ethylene glycol) (PEG) under the framework of quality by design, were…”
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The Effects of Apocynin on Monosodium Glutamate Induced Liver Damage of Rats
Published in Heliyon (01-07-2023)“…Monosodium glutamate (MSG) is found in refined foods. Apocynin (APO) is a selective NADPH oxidase (NOX) inhibitor. The aim of this experimental study was to…”
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Morphological evaluation of the effects of exercise on high-fat-diet-induced liver damage in rats
Published in The Turkish journal of gastroenterology (01-09-2020)“…Background/Aims: This study was aimed to investigate the protective effects of swimming on nonalcoholic fatty liver disease associated with…”
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Apocynin Ameliorates Monosodium Glutamate Induced Testis Damage by Impaired Blood-Testis Barrier and Oxidative Stress Parameters
Published in Life (Basel, Switzerland) (01-03-2023)“…the aim of this study was to investigate the effects of apocynin (APO) on hormone levels, the blood-testis barrier, and oxidative biomarkers in monosodium…”
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Synthesis of Tolmetin Hydrazide-Hydrazones and Discovery of a Potent Apoptosis Inducer in Colon Cancer Cells
Published in Archiv der Pharmazie (Weinheim) (01-10-2015)“…Tolmetin hydrazide and a novel series of tolmetin hydrazide–hydrazones 4a–l were synthesized in this study. The structures of the new compounds were determined…”
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Carbon Nanofiber-Sodium Alginate Composite Aerogels Loaded with Vitamin D: The Cytotoxic and Apoptotic Effects on Colon Cancer Cells
Published in Gels (01-07-2023)“…Colorectal cancer (CRC) is the fourth most commonly diagnosed cancer and the third leading cause of cancer-related deaths worldwide. A substantial body of…”
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Synthesis, Cytotoxicity, and Pro-Apoptosis Activity of Etodolac Hydrazide Derivatives as Anticancer Agents
Published in Archiv der Pharmazie (Weinheim) (01-05-2013)“…Etodolac hydrazide and a novel series of etodolac hydrazide‐hydrazones 3–15 and etodolac 4‐thiazolidinones 16–26 were synthesized in this study. The structures…”
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Effects of dapagliflozin in experimental sepsis model in rats
Published in Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES (01-05-2019)“…The aim of this study was to evaluate the possible protective effects of dapagliflozin in an experimental sepsis model in rats. Saline (1 mL/kg, p.o.) or…”
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Synthesis and characterization of celecoxib derivatives as possible anti-inflammatory, analgesic, antioxidant, anticancer and anti-HCV agents
Published in Molecules (Basel, Switzerland) (21-03-2013)“…A series of novel N-(3-substituted aryl/alkyl-4-oxo-1,3-thiazolidin-2-ylidene)-4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamides…”
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Synthesis and Anticancer and Antimicrobial Evaluation of Novel Ether-linked Derivatives of Ornidazole
Published in Turkish journal of pharmaceutical sciences (01-02-2020)“…Some novel 1-(2-methyl-5-nitro-1H-imidazol-1-yl)-3-(substituted phenoxy)propan-2-ol derivatives were designed and synthesized. Compounds were obtained by…”
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Growth Arrest-Specific 6 (Gas6) and TAM Receptors in Mouse Platelets
Published in Turkish journal of haematology (05-03-2015)“…Growth arrest-specific 6 (Gas6) is a newly discovered vitamin K-dependent protein, which is a ligand for TAM receptors [Tyro3 (Sky), Axl, and Mer] from the…”
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Exercise improves testicular morphology and oxidative stress parameters in rats with testicular damage induced by a high‐fat diet
Published in Andrologia (01-12-2022)“…Obesity and male infertility are problems that affect population. Exercise is a nonpharmacological way to reduce the negative health effects of obesity. The…”
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Fabrication and characterization of electrospun GelMA/PCL/CS nanofiber composites for wound dressing applications
Published in Journal of bioactive and compatible polymers (01-01-2023)“…In the present study, the effect of different ratios of GelMA concentration has been exhibited for wound dressing implementation by the electrospinning method…”
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In vitro electrically controlled amoxicillin release from 3D-printed chitosan/bismuth ferrite scaffolds
Published in European polymer journal (19-07-2023)“…[Display omitted] •Different concentrations of drug-loaded bismuth ferrite particles added to chitosan scaffolds were successfully produced with 3D printing…”
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A Novel Strategy as a Potential Rapid Therapy Modality in the Treatment of Corneal Ulcers: Fluconazole/Vancomycin Dual Drug‐Loaded Nanofibrous Patches
Published in Macromolecular materials and engineering (01-05-2023)“…Corneal ulcer, which is brought on by a breach in the epithelial barrier, is a dangerous infection of the avascular corneal stroma. New treatment strategies…”
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Investigation of the protective effect of gel incorporating Eugenia jambolana leaf extract on 5-fluorouracil-induced oral mucositis: an animal study
Published in Journal of cancer research and clinical oncology (01-08-2022)“…Purpose The study aimed to evaluate the possible preventive effect of two concentrations (3 and 5% w/w) of Eugenia jambolana (EJ) extract against 5-FU-induced…”
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