Search Results - "Öz, Yuva"

Robust 4C-seq data analysis to screen for regulatory DNA interactions by van de Werken, Harmen J G, Landan, Gilad, Holwerda, Sjoerd J B, Hoichman, Michael, Klous, Petra, Chachik, Ran, Splinter, Erik, Valdes-Quezada, Christian, Öz, Yuva, Bouwman, Britta A M, Verstegen, Marjon J A M, de Wit, Elzo, Tanay, Amos, de Laat, Wouter

“…A high-resolution 4C-seq protocol involving two restriction digests and a revised analysis pipeline allows robust detection of physical interactions between…”
Get full text

Nucleoside drugs induce cellular differentiation by caspase-dependent degradation of stem cell factors by Musch, Tanja, Oz, Yuva, Lyko, Frank, Breiling, Achim

“…Stem cell characteristics are an important feature of human cancer cells and play a major role in the therapy resistance of tumours. Strategies to target…”
Get full text

Building regulatory landscapes reveals that an enhancer can recruit cohesin to create contact domains, engage CTCF sites and activate distant genes by Rinzema, Niels J., Sofiadis, Konstantinos, Tjalsma, Sjoerd J. D., Verstegen, Marjon J. A. M., Oz, Yuva, Valdes-Quezada, Christian, Felder, Anna-Karina, Filipovska, Teodora, van der Elst, Stefan, de Andrade dos Ramos, Zaria, Han, Ruiqi, Krijger, Peter H. L., de Laat, Wouter

“…Developmental gene expression is often controlled by distal regulatory DNA elements called enhancers. Distant enhancer action is restricted to structural…”
Get full text