Search Results - "Öhman, K. P."

Food Does Not Affect the Pharmacokinetics of Tesaglitazar, a Novel Dual Peroxisome Proliferator-Activated Receptor α/γ Agonist by Samuelsson, S., Johansson, S., Halldórsdóttir, S., Stenhoff, H., Öhman, K. P.

“…Tesaglitazar is a dual peroxisome proliferator‐activated receptor (PPAR) α/γ agonist in development to treat lipid and glucose abnormalities associated with…”
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Serum angiotensin-converting enzyme activity correlates positively with plasma angiotensin II: a population-based study of ambulatory blood pressure and the renin-angiotensin system by NYSTRÖM, F, KARLBERG, B. E, ÖHMAN, K. P

“…A population-based study was performed in order to study the interrelationships of the circulating components of the renin-angiotensin system during basal…”
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Relationships between left ventricular mass and the renin–angiotensin system, catecholamines, insulin and leptin by Malmqvist, K., Öhman, K. P., Lind, L., Nyström, F., Kahan, T.

“… Malmqvist K, Öhman KP, Lind L, Nyström F, Kahan T (Karolinska Institutet Danderyd Hospital, Stockholm; Faculty of Health Sciences, Linköping; University…”
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Beta1‐adrenergic receptor gene polymorphisms and response to Beta1‐adrenergic receptor blockade in patients with essential hypertension by Karlsson, J., Lind, L., Hallberg, P., Michaëlsson, K., Kurland, L., Kahan, T., Malmqvist, K., Öhman, K. P., Nyström, F., Melhus, H.

“…Background: Studies suggest that the Ser49Gly and Arg389Gly polymorphisms in the β1‐adrenergic receptor might be of functional importance for the…”
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Plasma levels of cyclic GMP and endothelin in postmenopausal women with unstable coronary artery disease by N E Nielsen, J Ahlner, J Malmstedt, K P Öhman, E Swahn

“…Many women with typical anginal chest pain have normal coronary angiograms, which may be due to altered endothelial function. We evaluated the endothelial…”
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Pharmacokinetics and metabolism of tesaglitazar, a novel dual-acting peroxisome proliferator-activated receptor α/γ agonist, after a single oral and intravenous dose in humans by ERICSSON, H, HAMREN, B, BERGSTRAND, S, ELEBRING, M, FRYKLUND, L, HEIJER, M, ÖHMAN, K. P

“…The pharmacokinetics of tesaglitazar (GALIDA), a novel dual-acting peroxisome proliferator-activated receptor alpha and gamma agonist, were studied in eight…”
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Regression of left ventricular hypertrophy in human hypertension with irbesartan by Malmqvist, Karin, Kahan, Thomas, Edner, Magnus, Held, Claes, Hägg, Anders, Lind, Lars, Müller-Brunotte, Richard, Nyström, Fredrik, Öhman, K Peter, Osbakken, Mary D, Östergren, Jan

“…BACKGROUNDThe Swedish irbesartan left ventricular hypertrophy investigation versus atenolol (SILVHIA). OBJECTIVEAngiotensin II induces myocardial hypertrophy…”
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Angiotensin converting enzyme gene polymorphism predicts blood pressure response to angiotensin II receptor type 1 antagonist treatment in hypertensive patients by Kurland, Lisa, Melhus, Håkan, Karlsson, Julia, Kahan, Thomas, Malmqvist, Karin, Öhman, K Peter, Nyström, Fredrik, Hägg, Anders, Lind, Lars

“…OBJECTIVES To determine whether polymorphisms in the renin–angiotensin system can predict blood pressure-lowering response to antihypertensive treatment; more…”
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Gender‐specific association between preproendothelin‐1 genotype and reduction of systolic blood pressure during antihypertensive treatment‐‐‐results from the Swedish irbesartan left ventricular hypertrophy investigation versus atenolol (SILVHIA) by Hallberg, P., Karlsson, J., Lind, L., Michaëlsson, K., Kurland, L., Kahan, T., Malmqvist, K., Öhman, K. P., Nyström, F., Liljedahl, U., Syvänen, A. C., Melhus, H.

“…Background: Studies suggest that endothelin‐1 contributes to the pathogenesis of hypertension. A G5665T gene polymorphism of preproendothelin‐1 has been shown…”
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A single nucleotide polymorphism in the promoter region of the osteoprotegerin gene is related to intima-media thickness of the carotid artery in hypertensive patients. The Swedish Irbesartan Left Ventricular Hypertrophy Investigation vs Atenolol (SILVHIA) by Brändström, H, Stiger, F, Kahan, T, Melhus, H, Nyström, F, öHman, K P, Malmqvist, K, Lind, L, Kindmark, A

“…Osteoprotegerin (OPG) is a secreted member of the tumor necrosis factor receptor family, and in previous studies has been shown to regulate osteoclast activity…”
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Serum leptin concentrations in a normal population and in GH deficiency: negative correlation with testosterone in men and effects of GH treatment by Nyström, Fredrik, Ekman, Bertil, Österlund, Maria, Lindström, Torbjörn, Öhman, K. Peter, Arnqvist, Hans J.

“…OBJECTIVE To study relationships between leptin and factors regulating body composition as well as metabolic risk factors. Furthermore, to study the effects of…”
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Pitfalls in Doppler evaluation of diastolic function: insights from 3-dimensional magnetic resonance imaging by Fyrenius, A, Wigström, L, Bolger, A F, Ebbers, T, Ohman, K P, Karlsson, M, Wranne, B, Engvall, J

“…Ultrasound-Doppler assessment of diastolic function is subject to velocity errors caused by angle sensitivity and a fixed location of the sample volume. We…”
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Effect of Amlodipine Versus Felodipine Extended Release on 24-Hour Ambulatory Blood Pressure in Hypertension by Östergren, Jan, Isaksson, Hans, Brodin, Ulf, Schwan, Åke, Öhman, K.Peter

“…Amlodipine and felodipine are calcium antagonists of the dihydropyridine type. The elimination half-life of amlodipine is longer than that of felodipine. To…”
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Twenty-four hour ambulatory blood pressure in the population by Nyström, F, Malmström, O, Karlberg, B E, Ohman, K P

“…To establish a population-based 24-h ambulatory blood pressure (ABP) reference material with day/night mean BP calculated by standardized and true bedtimes. A…”
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Population-based reference values for IGF-I and IGF-binding protein-1: relations with metabolic and anthropometric variables by NYSTRÖM, F. H, ÖHMAN, P. K, EKMAN, B. A, ÖSTERLUND, M. K, KARLBERG, B. E, ARNQVIST, H. J

“…Abstract Population-based reference values for IGF-I and IGF-binding protein-1 (IGFBP-1) have been established. One hundred and one women and the same number…”
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Circulating Plasma Prekallikrein and Tissue Kallikrein in Normotensive and Hypertensive Humans: Effects of Angiotensin II Infusion by Öhman, K. P., Karlberg, B. E.

“…Kinins lower blood pressure but the stimuli leading to kinin generation and their origin are less well known. We administered angiotensin II in graded infusion…”
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A population-based study of plasma cyclic guanosine monophosphate: relations to age, atrial natriuretic factor and angiotensin-converting enzyme activity by Nyström, F. H., Ahlner, J., Karlberg, B. E., öhman, P. K.

“…In order to study the relations between plasma cyclic guanosine monophosphate (cGMP) and anthropometric variables, plasma atrial natriuretic factor (ANP) and…”
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Less difference between office and ambulatory blood pressure in women than in men both before and during antihypertensive treatment by Nyström, F H, Ohman, K P, Isaksson, H, Schwan, A, Ostergren, J

“…In 199 subjects (56% women) with a diastolic blood pressure (BP) of 95-115 mmHg, 5 mg of either amlodipine or felodipine extended release (ER) was given for 4…”
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A population-based study of the white-coat blood pressure effect: Positive correlation with plasma cortisol by Nyström, Fredrik, Aardal, Elisabeth, Öhman, K. Peter

“…We aimed to study the white-coat effect (WCE) of clinic blood pressure (BP) and its relation to plasma cortisol, neuropeptide Y (NPY) and demographic…”
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Thyroid hormone restores atrial stretch-induced secretion of atrial natriuretic peptide in hypophysectomized rats by Zamir, N, Slover, M, Ohman, K P

“…Acute blood volume expansion caused a rapid and profound release of atrial natriuretic peptides (ANP) from cardiac atria. The stimulated release of ANP was…”
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