Search Results - "Öberg, Christopher T."

Using Spinchem Rotating Bed Reactor Technology for Immobilized Enzymatic Reactions: A Case Study by Pithani, Subhash, Karlsson, Staffan, Emtenäs, Hans, Öberg, Christopher T

“…The practically and financially viable use of immobilized enzymes in the production of pharmaceutical and bulk chemicals requires highly catalytically active…”
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Synthesis, Biological Evaluation, and Structure–Activity Relationships of 2-[2-(Benzoylamino)benzoylamino]benzoic Acid Analogues as Inhibitors of Adenovirus Replication by Öberg, Christopher T, Strand, Mårten, Andersson, Emma K, Edlund, Karin, Tran, Nam Phuong Nguyen, Mei, Ya-Fang, Wadell, Göran, Elofsson, Mikael

“…2-[2-Benzoylamino)benzoylamino]benzoic acid (1) was previously identified as a potent and nontoxic antiadenoviral compound ( Antimicrob. Agents Chemother…”
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Arginine Binding Motifs: Design and Synthesis of Galactose-Derived Arginine Tweezers as Galectin-3 Inhibitors by Öberg, Christopher T, Leffler, Hakon, Nilsson, Ulf J

“…Anionic O2 derivatives of methyl 3-deoxy-3-(4-methylbenzamido)-1-thio-β-d-galactopyranoside have been synthesized as inhibitors against galectin-3. The…”
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Different affinity of galectins for human serum glycoproteins: Galectin-3 binds many protease inhibitors and acute phase proteins by Cederfur, Cecilia, Salomonsson, Emma, Nilsson, Jonas, Halim, Adnan, Öberg, Christopher T, Larson, Göran, Nilsson, Ulf J, Leffler, Hakon

“…Here we report the first survey of galectins binding to glycoproteins of human serum. Serum was subjected to affinity chromatography using immobilized…”
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Mutational Tuning of Galectin-3 Specificity and Biological Function by Salomonsson, Emma, Carlsson, Michael C., Osla, Veronica, Hendus-Altenburger, Ruth, Kahl-Knutson, Barbro, Öberg, Christopher T., Sundin, Anders, Nilsson, Rickard, Nordberg-Karlsson, Eva, Nilsson, Ulf J., Karlsson, Anna, Rini, James M., Leffler, Hakon

“…Galectins are defined by a conserved β-galactoside binding site that has been linked to many of their important functions in e.g. cell adhesion, signaling, and…”
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Affinity of galectin-8 and its carbohydrate recognition domains for ligands in solution and at the cell surface by Carlsson, Susanne, Öberg, Christopher T, Carlsson, Michael C, Sundin, Anders, Nilsson, Ulf J, Smith, David, Cummings, Richard D, Almkvist, Jenny, Karlsson, Anna, Leffler, Hakon

“…Galectin-8 has two different carbohydrate recognition domains (CRDs), the N-terminal Gal-8N and the C-terminal Gal-8C linked by a peptide, and has various…”
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Efficient and Expedient Two-Step Pyranose-Retaining Fluorescein Conjugation of Complex Reducing Oligosaccharides:  Galectin Oligosaccharide Specificity Studies in a Fluorescence Polarization Assay by Öberg, Christopher T, Carlsson, Susanne, Fillion, Eric, Leffler, Hakon, Nilsson, Ulf J

“…Fluorescence labeling of naturally occurring saccharides provides a tool for studying lectins. A practical and efficient two-step protocol for fluorescence…”
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Taloside Inhibitors of Galectin-1 and Galectin-3 by Collins, Patrick M., Öberg, Christopher T., Leffler, Hakon, Nilsson, Ulf J., Blanchard, Helen

“…Galectin‐1 and galectin‐3 have roles in cancer and inflammation. Galectin‐1 has recently emerged as a significant protein produced by tumour cells to promote…”
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Inhibition of galectins with small molecules by Oberg, Christopher T, Leffler, Hakon, Nilsson, Ulf J

“…Evidence that the galectin family of proteins plays crucial roles in cancer, inflammation, and immunity has accumulated over the last decade. The galectins…”
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Syntheses of pseudoceramines A-D and a new synthesis of spermatinamine, bromotyrosine natural products from marine sponges by Hillgren, J Mikael, Oberg, Christopher T, Elofsson, Mikael

“…Herein we report the total syntheses of pseudoceramine A-D (2-5) and spermatinamine (1) isolated from the marine sponge Pseudoceratina sp. Direct acyl…”
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2-[4,5-Difluoro-2-(2-Fluorobenzoylamino)-Benzoylamino]Benzoic Acid, an Antiviral Compound with Activity against Acyclovir-Resistant Isolates of Herpes Simplex Virus Types 1 and 2 by STRAND, Mårten, ISLAM, Koushikul, EDLUND, Karin, ÖBERG, Christopher T, ALLARD, Annika, BERGSTRÖM, Tomas, MEI, Ya-Fang, ELOFSSON, Mikael, WADELL, Göran

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Arene-Anion Based Arginine-Binding Motif on a Galactose Scaffold: Structure-Activity Relationships of Interactions with Arginine-Rich Galectins by Öberg, Christopher T., Noresson, Ann-Louise, Leffler, Hakon, Nilsson, Ulf J.

“…Two series of C3‐benzamido and O2‐anion‐substituted galactopyranosides were synthesized and studied as binders to arginine‐rich proteins galectin‐1, ‐3, ‐7,…”
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Synthesis of 3-amido-3-deoxy-β- d-talopyranosides: all- cis-substituted pyranosides as lectin inhibitors by Öberg, Christopher T., Noresson, Ann-Louise, Leffler, Hakon, Nilsson, Ulf J.

“…3-Deoxy-3-amino-β- d-talopyranosides have been synthesized for the first time. The amines were obtained from galactopyranosides through 2,3-anhydrogulosides…”
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Inhibition mechanism of human galectin‐7 by a novel galactose‐benzylphosphate inhibitor by Masuyer, Geoffrey, Jabeen, Talat, Öberg, Christopher T., Leffler, Hakon, Nilsson, Ulf J., Acharya, K. Ravi

“…Galectins are involved in many cellular processes due to their ability to bind carbohydrates. Understanding their functions has shown the necessity for potent…”
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Protein subtype-targeting through ligand epimerization: Talose-selectivity of galectin-4 and galectin-8 by Öberg, Christopher T., Blanchard, Helen, Leffler, Hakon, Nilsson, Ulf J.

“…Galectin-4 C-terminal domain and galectin-8 N-terminal domain were found to prefer the d-talopyranose configuration to the natural ligand d-galactopyranose…”
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Synthesis of 2-(2-aminopyrimidine)-2,2-difluoroethanols as potential bioisosters of salicylidene acylhydrazides by Dahlgren, Markus K, Oberg, Christopher T, Wallin, Erika A, Janson, Pär G, Elofsson, Mikael

“…Salicylidene acylhydrazides are inhibitors of type III secretion in several gram-negative pathogens. To further develop the salicylidene acylhydrazides,…”
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Synthesis of 3-azido-3-deoxy-β- d-galactopyranosides by Öberg, Christopher T., Noresson, Ann-Louise, Delaine, Tamara, Larumbe, Amaia, Tejler, Johan, von Wachenfeldt, Henrik, Nilsson, Ulf J.

“…Three efficient routes to 3-azido-3-deoxy-β- d-galactopyranosides were developed relying on a double inversion protocol at C3. Two of the routes were…”
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Total Synthesis of the Resveratrol Oligomers (±)-Ampelopsin B and (±)-ϵ-Viniferin by Lindgren, Anders E. G., Öberg, Christopher T., Hillgren, J. Mikael, Elofsson, Mikael

“…The total synthesis of the resveratrol dimers (±)‐ampelopsin B and (±)‐ϵ‐viniferin is reported. Highlights of the approach include the use of cyclopropylmethyl…”
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2-[4,5-Difluoro-2-(2-fluorobenzoylamino)-benzoylamino]benzoic acid, an antiviral compound with activity against acyclovir-resistant isolates of herpes simplex virus type 1 and 2 by Strand, Mårten, Islam, Koushikul, Edlund, Karin, Öberg, Christopher T, Allard, Annika, Bergström, Tomas, Mei, Ya-Fang, Elofsson, Mikael, Wadell, Göran

“…Herpes simplex viruses (HSV-1 and HSV-2) are responsible for life-long latent infections in humans, with periods of viral reactivation associated with…”
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Total Synthesis of the Resveratrol Oligomers (+/-)-Ampelopsin B and (+/-)-E-Viniferin by Lindgren, Anders E. G., Oberg, Christopher T., Hillgren, J. Mikael, Elofsson, Mikael

“…The total synthesis of the resveratrol dimers (+/-)-ampelopsin B and (+/-)-E-viniferin is reported. Highlights of the approach include the use of…”
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