Search Results - "ÖKTEM, Gülperi"
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Effect of Flavopiridol on Cell Cycle, Apoptosis and Biomolecule Structure Changes in Breast Cancer Stem Cells
Published in Bezmialem science (01-07-2020)“…Objective: Cancer stem cells (CSCs) are a small population in cancer, which are responsible for therapeutic resistance, relapse and metastasis. Flavopiridol…”
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Different mRNA and Protein Expression of Versican in TGF-β1-treated Prostate Cancer Cells
Published in Forbes Tıp Dergisi (05-08-2022)“…Objective: Cellular heterogeneity of tumors stems from cell populations expressing a unique set of proteins defective genetic and epigenetic networks. It is…”
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Immunohistochemical Analysis of Inducible and Endothelial Forms of Nitric Oxide Synthase in Cyclosporin A‐Induced Gingival Overgrowth
Published in Journal of periodontology (1970) (01-10-2009)“…Background: The contribution of nitric oxide (NO) to immune response and matrix degradation in the periodontal environment suggests a role for NO and…”
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Immunohistochemical expression of connexin 43 and occludin in the rat testis after epididymal and vasal ligation
Published in Fertility and sterility (01-07-2008)“…Objective To describe the effects of epididymal and vasal ligation, in an experimental rat model, by using connexin 43 and occludin immunohistochemistry as…”
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Prostat Kanseri Kök Hücrelerinde Zoledronik Asit Tedavisinin Hücre Adezyon Moleküllerine Etkisi
Published in T.C. Uludağ Üniversitesi Tıp Fakültesi dergisi (15-09-2022)“…Prostat kanserinin tanı ve tedavisine yönelik birçok alanda ilerleme sağlanabilmesine rağmen hastalık bazı vakalar için ölümcül olma niteliğini sürdürmektedir…”
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İnsan diş pulpası kaynaklı mezenkimal kök hücrelerin meme kanseri kök hücreleri üzerine etkisi
Published in Ege tıp dergisi (18-09-2023)“…Amaç: Kanser kök hücreleri; kendini yenileyebilen, farklılaşma kapasitesi yüksek ve uzun süreli proliferasyon ile normal dokuya invazyon kabiliyeti olan…”
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Enteral resveratrol supplementation attenuates intestinal epithelial inducible nitric oxide synthase activity and mucosal damage in experimental necrotizing enterocolitis
Published in Journal of pediatric surgery (01-10-2007)“…Abstract Background/Purpose The release of various enzymes including inducible nitric oxide synthase (iNOS) leads to enterocyte apoptosis through free nitrogen…”
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IR spektroskopi kullanılarak in vitro meme kanser kök hücrelerinin araştırılması
Published in Ege tıp dergisi (30-09-2020)“…Amaç: Kanser kök hücreleri (KKH), tümör içinde kendi kendilerini yenileme ve diğer hücre tiplerine farklılaşabilme kapasitesi sebebiyle tümörün başlaması,…”
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ZNF304 gen ifadesinde artış ve CXCR4’de azalma ile prostat kanserinde anoikis değişebilir
Published in Ege tıp dergisi (14-09-2018)“…Amaç: Prostat kanser hücre hattı (DU145) ve prostat normal epitel hücre hatları (RWPE) arasında anoikis mekanizmasını arttıracak veya inhibe edebilecek…”
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Midkine downregulation increases the efficacy of quercetin on prostate cancer stem cell survival and migration through PI3K/AKT and MAPK/ERK pathway
Published in Biomedicine & pharmacotherapy (01-11-2018)“…[Display omitted] To examine the functions of growth factor midkine (MK) and a flavonoid quercetin on survival, apoptosis and migration of prostate cancer…”
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Constructive effect of exogenous melatonin against osteoporosis after ovariectomy in rats
Published in Analytical and quantitative cytology and histology (01-10-2007)“…To analyze histomorphometric, densitometric and biochemical effects of melatonin on osteoporosis in ovariectomized rats. Wistar rats were divided into 6…”
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Evaluation of chondrogenesis and osteogenesis via Wnt/β-Catenin, S100 immunoexpression and histomorphometry in fetal rats following maternal uterine artery ligation
Published in Ege tıp dergisi (13-03-2020)“…Aim: The aim of this study is to investigate the effects of intrauterine growth retardation depending on maternal uterine artery ligation, Wnt/β-catenin and…”
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Zoledronik asit uygulamasının meme kanseri hücre hattı (mcf 7) kanser kök hücrelerinin üzerine otofaji gen seviyesindeki etkilerinin araştırılması
Published in Ege tıp dergisi (14-03-2019)“…Amaç: Zoledronik asit (ZA) uygulanmış meme kanser kök hücrelerinde (KKH), kanser kök hücresi ve otofaji ile ilişkili gen ekspresyonlarındaki farklılıkları…”
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Glycogen synthase kinase-3 inhibition in glioblastoma multiforme cells induces apoptosis, cell cycle arrest and changing biomolecular structure
Published in Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy (15-02-2019)“…Glioblastoma multiforme (GBM) is the most malignant and aggressive primary human brain tumors. The regulatory pathways of apoptosis are altered in GBMs,…”
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Sonic hedgehog signaling is associated with resistance to zoledronic acid in CD133high/CD44high prostate cancer stem cells
Published in Molecular biology reports (01-04-2021)“…Cancer stem cells (CSCs) are a unique population that has been linked to drug resistance and metastasis and recurrence of prostate cancer. The sonic hedgehog…”
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Fourier dönüşümü kızılötesi spektroskopisi ile CD133+/CD44+ prostat kanser kök hücrelerinin iki boyutlu ve üç boyutlu ortamdaki hücresel farklılıklarının belirlemesi
Published in Dokuz Eylül Üniversitesi Tıp Fakültesi dergisi (01-01-2019)“…Amaç: Sferoid kültürleri, hücrelerin kendi iç dinamikleri ve diğer hücrelerle olan etkileşimleri açısından tek tabakalı kültürlere kıyasla tümör dokusunun…”
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Enhanced G2/M Arrest, Caspase Related Apoptosis and Reduced E-Cadherin Dependent Intercellular Adhesion by Trabectedin in Prostate Cancer Stem Cells
Published in PloS one (20-10-2015)“…Trabectedin (Yondelis, ET-743) is a marine-derived tetrahydroisoquinoline alkaloid. It is originally derived from the Caribbean marine tunicate Ecteinascidia…”
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Doxorubicin Induced Nephrotoxicity: Protective Effect of Nicotinamide
Published in International Journal of Cell Biology (2011)“…Introduction. Nephrotoxicity is one of the important side effects of anthracycline antibiotics. The aim of this study was to investigate the effects of…”
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Neuroprotective Effect of Intrastriatal Caffeic Acid Phenethyl Ester Treatment in 6-OH Dopamine Model of Parkinson’s Disease in Rats
Published in Parkinson's disease (2021)“…Parkinson’s disease (PD) is the second most common neurodegenerative disorder, and the main cause of PD is still not known. Until now, no cure for Parkinson’s…”
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