Search Results - "ÖHLER, Leopold"

Efficacy and safety of everolimus plus exemestane in patients with HR+, HER2− advanced breast cancer progressing on/after prior endocrine therapy in routine clinical practice: Primary results from the non-interventional study, STEPAUT by Steger, Guenther G., Egle, Daniel, Bartsch, Rupert, Pfeiler, Georg, Petru, Edgar, Greil, Richard, Helfgott, Ruth, Marth, Christian, Öhler, Leopold, Hubalek, Michael, Lang, Alois, Tinchon, Christoph, Haslbauer, Ferdinand, Redl, Andreas, Hock, Karin, Hennebelle, Mathias, Mraz, Bernhard, Gnant, Michael

“…STEPAUT, an Austrian non-interventional study, evaluated the safety and efficacy of everolimus plus exemestane in patients with hormone receptor-positive…”
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Molecular Basis and Clinical Application of Growth-Factor-Independent In Vitro Myeloid Colony Formation in Chronic Myelomonocytic Leukemia by Geissler, Klaus, Jäger, Eva, Barna, Agnes, Gurbisz, Michael, Graf, Temeida, Graf, Elmir, Nösslinger, Thomas, Pfeilstöcker, Michael, Machherndl-Spandl, Sigrid, Stauder, Reinhard, Zebisch, Armin, Sill, Heinz, Öhler, Leopold, Kusec, Rajko, Hörmann, Gregor, Valent, Peter

“…We have originally reported that colony-forming units granulocyte/macrophage (CFU-GM) formation is an in vitro feature of chronic myelomonocytic leukemia…”
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Nab-paclitaxel and gemcitabine or FOLFIRINOX as first-line treatment in patients with unresectable adenocarcinoma of the pancreas: does sequence matter? by Vogl, Ursula M, Andalibi, Haleh, Klaus, Alexander, Vormittag, Laurenz, Schima, Wolfgang, Heinrich, Bettina, Kafka, Alice, Winkler, Thomas, Öhler, Leopold

“…Locally advanced or metastatic adenocarcinoma of the pancreas remains - despite the implementation of new chemotherapy protocols - a disease with short overall…”
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Clinical meaning and implications of serum hemoglobin levels in patients with rheumatoid arthritis by Padjen, Ivan, Öhler, Leopold, Studenic, Paul, Woodworth, Thasia, Smolen, Josef, Aletaha, Daniel

“…Abstract Objective Anemia is a common problem in rheumatoid arthritis (RA), associated with radiographic progression and disability. We explored the…”
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Transferrin receptor 1 is a cellular receptor for human heme-albumin by Jennifer, Brell, Berg, Verena, Modak, Madhura, Puck, Alexander, Seyerl-Jiresch, Maria, Künig, Sarojinidevi, Zlabinger, Gerhard J., Steinberger, Peter, Chou, Janet, Geha, Raif S., Öhler, Leopold, Yachie, Akihiro, Choe, Hyeryun, Kraller, Markus, Stockinger, Hannes, Stöckl, Johannes

“…Iron is essential for living cells. Uptake of iron-loaded transferrin by the transferrin receptor 1 (CD71, TFR) is a major but not sufficient mechanism and an…”
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Impact of age on the cumulative risk of transformation in patients with chronic myelomonocytic leukaemia by Machherndl‐Spandl, Sigrid, Jäger, Eva, Barna, Agnes, Gurbisz, Michael, Marschon, Renate, Graf, Temeida, Graf, Elmir, Geissler, Christoph, Hoermann, Gregor, Nösslinger, Thomas, Pfeilstöcker, Michael, Bettelheim, Peter, Zach, Otto, Weltermann, Ansgar, Heibl, Sonja, Thaler, Josef, Zebisch, Armin, Sill, Heinz, Stauder, Reinhard, Webersinke, Gerald, Kusec, Rajko, Ulsperger, Ernst, Schneeweiss, Bruno, Öhler, Leopold, Germing, Ulrich, Valent, Peter, Tüchler, Heinz, Geissler, Klaus

“…In older patients with chronic myelomonocytic leukaemia (CMML) and limited life expectancy due to age and or comorbidities, it is particularly important to…”
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Fifth-line HER2-directed therapy for metastatic adenocarcinoma of the gastroesophageal junction: A case report by Roider-Schur, Sophie, Machat, Sybille, Öhler, Leopold

“…Summary Evaluation of HER2 status and programmed death-ligand 1 (PD-L1) combined positive score (CPS) is mandatory in all patients with HER2-positive…”
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Safety and effectiveness of regorafenib in patients with metastatic colorectal cancer in routine clinical practice in the prospective, observational CORRELATE study by Ducreux, Michel, Petersen, Lone Nørgård, Öhler, Leopold, Bergamo, Francesca, Metges, Jean-Philippe, de Groot, Jan Willem, Wang, Jaw-Yuan, García Paredes, Beatriz, Dochy, Emmanuelle, Fiala-Buskies, Sabine, Cervantes, Andrés, O'Connor, Juan Manuel, Falcone, Alfredo

“…Regorafenib prolonged overall survival (OS) versus placebo in patients with treatment-refractory metastatic colorectal cancer (mCRC) in phase III trials. We…”
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Interleukin-10 Inhibits Erythropoietin-Independent Growth of Erythroid Bursts in Patients With Polycythemia Vera by Geissler, Klaus, Öhler, Leopold, Födinger, Manuela, Kabrna, Eva, Kollars, Marietta, Skoupy, Sonja, Lechner, Klaus

“…In polycythemia vera (PV) erythroid colonies that grow in vitro in the absence of exogenous erythropoietin (EPO) arise from the abnormal clone that is…”
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Myelomonocytic skewing in chronic myelomonocytic leukemia: phenotypic, molecular and biologic features and impact on survival by Geissler, Klaus, Jäger, Eva, Barna, Agnes, Graf, Temeida, Graf, Elmir, Öhler, Leopold, Hoermann, Gregor, Valent, Peter

“…Background Myelomonocytic skewing is considered as a key pathophysiologic phenomenon in chronic myelomonocytic leukemia (CMML), but its prevalence and…”
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Unerwartete COVID-19-Pneumonie beim MDCT-Re-Staging eines Patienten mit Rektumkarzinom by Schima, Wolfgang, Öhler, Leopold, Eisenhuber-Stadler, Edith

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Phase III FIRE-4 study (AIO KRK-0114): Influence of baseline liquid biopsy results in first-line treatment efficacy of FOLFIRI/cetuximab in patients with tissue RAS-WT mCRC by Stintzing, Sebastian, Heinemann, Volker, Fischer von Weikersthal, Ludwig, Fuchs, Martin, Kaiser, Florian, Heinrich, Kathrin, Modest, Dominik Paul, Hofheinz, Ralf Dieter, Decker, Thomas, Gerger, Armin, Angermeier, Stefan, Rumpold, Holger, Öhler, Leopold, Gruenberger, Birgit, Niedersuess-Beke, Dora, Winder, Thomas, Trojan, Joerg, Prager, Gerald W., Baraniskin, Alexander, Klein-Scory, Susanne

“…3507 Background: FIRE-4 (AIO KRK-0114) is performed in RAS wild-type (wt) mCRC patients. This randomized study tests the efficacy of early switch maintenance…”
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Phase III FIRE-4 study (AIO KRK-0114): Evaluation of first-line treatment efficacy of FOLFIRI/cetuximab in patients with RAS-WT mCRC receiving the first cycle of treatment with chemotherapy only by Stintzing, Sebastian, Fischer von Weikersthal, Ludwig, Fuchs, Martin, Kaiser, Florian, Heinrich, Kathrin, Modest, Dominik Paul, Hofheinz, Ralf-Dieter, Decker, Thomas, Gerger, Armin, Angermeier, Stefan, Rumpold, Holger, Dickhut, Andreas, Öhler, Leopold, Gruenberger, Birgit, Niedersuess-Beke, Dora, Sandmann, Matthias, Winder, Thomas, Trojan, Joerg, Prager, Gerald, Heinemann, Volker

“…100 Background: FIRE-4 (AIO KRK-0114) is performed in RAS wild-type (wt) mCRC patients. This randomized study tests the efficacy of early switch maintenance…”
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545 INCIDENCE OF INVOLVEMENT OF PARATRACHEAL LYMPHNODES IN SIEWERT AEG-I TUMORS by Zacherl, Johannes, Radlspöck, Wolfgang, Albinni, Said, Höfle, Cordula, Kertesz, Viktoria, Öhler, Leopold, Schima, Wolfgang, Sitzwohl, Christian, Braun, Otto

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Randomized study to investigate a switch maintenance concept with 5-FU plus bevacizumab after FOLFIRI plus cetuximab induction treatment versus continued treatment with FOLFIRI plus cetuximab: Report of a secondary endpoint of the phase-III FIRE-4 study (AIO KRK-0114) by Stintzing, Sebastian, von Weikersthal, Ludwig, Fuchs, Martin, Kaiser, Florian, Heinrich, Kathrin, Modest, Dominik Paul, Hofheinz, Ralf, Decker, Thomas, Gerger, Armin, Angermeier, Stefan, Rumpold, Holger, Dickhut, Andreas, Öhler, Leopold, Gruenberger, Birgit, Niedersuess -Beke, Dora, Sandmann, Matthias, Winder, Thomas, Kasper, Stefan, Prager, Gerald, Heinemann, Volker

“…3519 Background: FIRE-4 (AIO KRK-0114) is performed in RAS-wild-type (wt) mCRC patients. This randomized study tests the efficacy of early switch maintenance…”
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Multistep pathogenesis of chronic myelomonocytic leukemia in patients by Geissler, Klaus, Jäger, Eva, Barna, Agnes, Gurbisz, Michael, Marschon, Renate, Graf, Temeida, Nösslinger, Thomas, Pfeilstöcker, Michael, Machherndl‐Spandl, Sigrid, Stauder, Reinhard, Zebisch, Armin, Sill, Heinz, Öhler, Leopold, Kusec, Rajko, Hoermann, Gregor, Valent, Peter

“…Background A multistep pathogenesis of myeloid leukemia including mutations in epigenetic, spliceosome, and signaling genes has been recently demonstrated in a…”
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REGO-ACT: assessment of physical activity during treatment with regorafenib for metastatic colorectal cancer by Piringer, Gudrun, Vormittag, Laurenz, Öhler, Leopold, Grünberger, Birgit, Meran, Johannes, Moshammer, Marlies, Andel, Johannes, Eisterer, Wolfgang, Trommet, Vera, Thaler, Josef

“…Summary Background A frequent side effect of the multikinase inhibitor regorafenib is fatigue. Physical activity has shown potential in reducing cancer-related…”
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PS01.177: ERAS HYBRID IVOR LEWIS ESOPHAGECTOMY by Zacherl, Johannes, Albinni, Said, Radlspöck, Wolfgang, Kertesz, Viktoria, Lechmann, Andrea, Platter, Thomas, Vavrovsky, Gerhard, Öhler, Leopold

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Outcomes by tumor location in patients with metastatic colorectal cancer (mCRC) treated with regorafenib (REG): Final analysis from the prospective, observational CORRELATE study by Ducreux, Michel, Petersen, Lone Nørgård, Öhler, Leopold, Bergamo, Francesca, Metges, Jean-Philippe, de Groot, Jan Willem, Wang, Chao-Yuan, García-Paredes, Beatriz, Dochy, Emmanuelle, Fiala-Buskies, Sabine, Cervantes, Andres, O'Connor, Juan Manuel, Falcone, Alfredo

“…Abstract only 539 Background: The anatomical location of the primary tumor has been associated with different prognosis and outcomes in mCRC. REG significantly…”
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Evaluation of Prognostic Immune Signatures in Patients with Breast, Colorectal and Pancreatic Cancer Receiving Chemotherapy by Vogl, Ursula M, Öhler, Leopold, Rasic, Masa, Frischer, Josa M, Modak, Madhura, Stöckl, Johannes

“…CD97 is a member of the epidermal growth factor-seven transmembrane (EGF-TM7) receptor family and is dominantly expressed on immune cells and in a variety of…”
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