Search Results - "Òlaso, Gloria"

Histone h3 glutathionylation in proliferating mammalian cells destabilizes nucleosomal structure by García-Giménez, José Luis, Òlaso, Gloria, Hake, Sandra B, Bönisch, Clemens, Wiedemann, Sonja M, Markovic, Jelena, Dasí, Francisco, Gimeno, Amparo, Pérez-Quilis, Carme, Palacios, Oscar, Capdevila, Mercè, Viña, José, Pallardó, Federico V

“…Here we report that chromatin, the complex and dynamic eukaryotic DNA packaging structure, is able to sense cellular redox changes. Histone H3, the only…”
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Impact of supplementation with vitamins B6, B12, and/or folic acid on the reduction of homocysteine levels in patients with mild cognitive impairment: A systematic review by Olaso‐Gonzalez, Gloria, Inzitari, Marco, Bellelli, Giuseppe, Morandi, Alessandro, Barcons, Núria, Viña, José

“…Hyperhomocysteinemia is an independent predictor of the risk for cognitive decline and may be a result of low levels of vitamins B12, B6, and folate. Previous…”
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Multimodal strategy to rescue the brain in mild cognitive impairment: Ketogenic oral nutrition supplementation with B vitamins and aerobic exercise by Cunnane, Stephen C., Swerdlow, Russell H., Inzitari, Marco, Olaso‐Gonzalez, Gloria, Viña, José

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Oxidative Stress Is Related to Frailty, Not to Age or Sex, in a Geriatric Population: Lipid and Protein Oxidation as Biomarkers of Frailty by Inglés, Marta, Gambini, Juan, Carnicero, Jose A., García-García, Francisco J., Rodríguez-Mañas, Leocadio, Olaso-González, Gloria, Dromant, Mar, Borrás, Consuelo, Viña, Jose

“…Objectives To ascertain whether indicators of oxidative damage to lipids (malondialdehyde (MDA)) and proteins (protein carbonylation) are biomarkers of…”
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Anti-Inflammatory Properties of Diet: Role in Healthy Aging by Stromsnes, Kristine, Correas, Angela G., Lehmann, Jenny, Gambini, Juan, Olaso-Gonzalez, Gloria

“…Inflammation is a physiological process involved in the defenses of the body and the repair of tissues. It is acutely activated by infections, trauma, toxins,…”
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Pharmacological Properties of Polyphenols: Bioavailability, Mechanisms of Action, and Biological Effects in In Vitro Studies, Animal Models, and Humans by Stromsnes, Kristine, Lagzdina, Rudite, Olaso-Gonzalez, Gloria, Gimeno-Mallench, Lucia, Gambini, Juan

“…Drugs are bioactive compounds originally discovered from chemical structures present in both the plant and animal kingdoms. These have the ability to interact…”
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Electrostatic Control of the Photoisomerization Efficiency and Optical Properties in Visual Pigments: On the Role of Counterion Quenching by Tomasello, Gaia, Olaso-González, Gloria, Altoè, Piero, Stenta, Marco, Serrano-Andrés, Luis, Merchán, Manuela, Orlandi, Giorgio, Bottoni, Andrea, Garavelli, Marco

“…Hybrid QM(CASPT2//CASSCF/6−31G*)/MM(Amber) computations have been used to map the photoisomerization path of the retinal chromophore in Rhodopsin and explore…”
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The Role of Adenine Excimers in the Photophysics of Oligonucleotides by Olaso-González, Gloria, Merchán, Manuela, Serrano-Andrés, Luis

“…Energies and structures of different arrangements of the stacked adenine homodimer have been computed at the ab initio CASPT2 level of theory in isolation and…”
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Molecular Basis of DNA Photodimerization: Intrinsic Production of Cyclobutane Cytosine Dimers by Roca-Sanjuán, Daniel, Olaso-González, Gloria, González-Ramírez, Israel, Serrano-Andrés, Luis, Merchán, Manuela

“…Based on CASPT2 results, the present contribution establishes for the first time that cytosine photodimer formation (CC) is mediated along the triplet and…”
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Physical exercise in the prevention and treatment of Alzheimer's disease by De la Rosa, Adrian, Olaso-Gonzalez, Gloria, Arc-Chagnaud, Coralie, Millan, Fernando, Salvador-Pascual, Andrea, García-Lucerga, Consolacion, Blasco-Lafarga, Cristina, Garcia-Dominguez, Esther, Carretero, Aitor, Correas, Angela G., Viña, Jose, Gomez-Cabrera, Mari Carmen

“…•Low levels of physical activity are a risk factor associated with Alzheimer's disease.•Older adults who exercise are more likely to maintain…”
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Relationship between Diet, Microbiota, and Healthy Aging by Sanchez-Morate, Elisa, Gimeno-Mallench, Lucia, Stromsnes, Kristine, Sanz-Ros, Jorge, Román-Domínguez, Aurora, Parejo-Pedrajas, Sergi, Inglés, Marta, Olaso, Gloria, Gambini, Juan, Mas-Bargues, Cristina

“…Due to medical advances and lifestyle changes, population life expectancy has increased. For this reason, it is important to achieve healthy aging by reducing…”
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Glucose 6‐P dehydrogenase delays the onset of frailty by protecting against muscle damage by Arc‐Chagnaud, Coralie, Salvador‐Pascual, Andrea, Garcia‐Dominguez, Esther, Olaso‐Gonzalez, Gloria, Correas, Angela G., Serna, Eva, Brioche, Thomas, Chopard, Angele, Fernandez‐Marcos, Pablo J., Serrano, Manuel, Serrano, Antonio L., Muñoz‐Cánoves, Pura, Sebastiá, Vicente, Viña, Jose, Gomez‐Cabrera, Mari Carmen

“…Background Frailty is a major age‐associated syndrome leading to disability. Oxidative damage plays a significant role in the promotion of frailty. The…”
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Redox-related biomarkers in physical exercise by Gomez-Cabrera, Mari Carmen, Carretero, Aitor, Millan-Domingo, Fernando, Garcia-Dominguez, Esther, Correas, Angela G, Olaso-Gonzalez, Gloria, Viña, Jose

“…Research in redox biology of exercise has made considerable advances in the last 70 years. Since the seminal study of George Pake's group calculating the…”
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Toward the understanding of DNA fluorescence: the singlet excimer of cytosine by Olaso-González, Gloria, Roca-Sanjuán, Daniel, Serrano-Andrés, Luis, Merchán, Manuela

“…By using the multiconfigurational second-order perturbation method CASPT2, including corrections for the basis set superposition error, the lowest-singlet…”
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Glucose 6 phosphate dehydrogenase overexpression rescues the loss of cognition in the double transgenic APP/PS1 mouse model of Alzheimer’s disease by Correas, Angela G., Olaso-Gonzalez, Gloria, Roca, Marta, Blanco-Gandía, Mari Carmen, Nascimento, Carla, Lahoz, Agustin, Rodriguez-Arias, Marta, Miñarro, José, Gomez-Cabrera, Mari Carmen, Viña, José

“…Mice models of Alzheimer's disease (APP/PS1) typically experience cognitive decline with age. G6PD overexpressing mice (G6PD-Tg) exhibit better protection from…”
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Inhibition of xanthine oxidase by allopurinol prevents skeletal muscle atrophy: role of p38 MAPKinase and E3 ubiquitin ligases by Derbre, Frederic, Ferrando, Beatriz, Gomez-Cabrera, Mari Carmen, Sanchis-Gomar, Fabian, Martinez-Bello, Vladimir E, Olaso-Gonzalez, Gloria, Diaz, Ana, Gratas-Delamarche, Arlette, Cerda, Miguel, Viña, Jose

“…Alterations in muscle play an important role in common diseases and conditions. Reactive oxygen species (ROS) are generated during hindlimb unloading due, at…”
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Real-Life Outcomes of a Multicomponent Exercise Intervention in Community-Dwelling Frail Older Adults and Its Association with Nutritional-Related Factors by Millan-Domingo, Fernando, Tarazona-Santabalbina, Francisco Jose, Carretero, Aitor, Olaso-Gonzalez, Gloria, Viña, Jose, Gomez-Cabrera, Maria Carmen

“…Most of the studies on physical exercise in older adults have been conducted through randomized clinical trials performed under tight experimental conditions…”
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Allopurinol partially prevents disuse muscle atrophy in mice and humans by Ferrando, Beatriz, Gomez-Cabrera, Mari Carmen, Salvador-Pascual, Andrea, Puchades, Carlos, Derbré, Frederic, Gratas-Delamarche, Arlette, Laparre, Ludovic, Olaso-Gonzalez, Gloria, Cerda, Miguel, Viosca, Enrique, Alabajos, Ana, Sebastiá, Vicente, Alberich-Bayarri, Angel, García-Castro, Fabio, Viña, Jose

“…Disuse muscle wasting will likely affect everyone in his or her lifetime in response to pathologies such as joint immobilization, inactivity or bed rest. There…”
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Metabolomic analysis of long-term spontaneous exercise in mice suggests increased lipolysis and altered glucose metabolism when animals are at rest by Monleon, Daniel, Garcia-Valles, Rebeca, Morales, Jose Manuel, Brioche, Thomas, Olaso-Gonzalez, Gloria, Lopez-Grueso, Raul, Gomez-Cabrera, Mari Carmen, Viña, Jose

“…Exercise has been associated with several beneficial effects and is one of the major modulators of metabolism. The working muscle produces and releases…”
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Glucose 6-P Dehydrogenase—An Antioxidant Enzyme with Regulatory Functions in Skeletal Muscle during Exercise by García-Domínguez, Esther, Carretero, Aitor, Viña-Almunia, Aurora, Domenech-Fernandez, Julio, Olaso-Gonzalez, Gloria, Viña, Jose, Gomez-Cabrera, Mari Carmen

“…Hypomorphic Glucose 6-P dehydrogenase (G6PD) alleles, which cause G6PD deficiency, affect around one in twenty people worldwide. The high incidence of G6PD…”
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