Search Results - "Íñiguez, Miguel A"
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Nitro-oleic acid regulates T cell activation through post-translational modification of calcineurin
Published in Proceedings of the National Academy of Sciences - PNAS (24-01-2023)“…Nitro-fatty acids (NO -FAs) are unsaturated fatty acid nitration products that exhibit anti-inflammatory actions in experimental mouse models of autoimmune and…”
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Cyclooxygenase-2 and Prostaglandin E2 Signaling through Prostaglandin Receptor EP-2 Favor the Development of Myocarditis during Acute Trypanosoma cruzi Infection
Published in PLoS neglected tropical diseases (2015)“…Inflammation plays an important role in the pathophysiology of Chagas disease, caused by Trypanosoma cruzi. Prostanoids are regulators of homeostasis and…”
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Regulation of Cyclooxygenase-2 Expression in Human T Cells by Glucocorticoid Receptor-Mediated Transrepression of Nuclear Factor of Activated T Cells
Published in International journal of molecular sciences (31-10-2022)“…Cyclooxygenase (COX) is the key enzyme in prostanoid synthesis from arachidonic acid (AA). Two isoforms, named COX-1 and COX-2, are expressed in mammalian…”
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Involvement of PGE2 and the cAMP signalling pathway in the up-regulation of COX-2 and mPGES-1 expression in LPS-activated macrophages
Published in Biochemical journal (15-04-2012)“…PG (prostaglandin) E2 plays an important role in the modulation of the immune response and the inflammatory process. In the present study, we describe a PGE2…”
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Echolocation behavior of franciscana dolphins ( Pontoporia blainvillei ) in the wild
Published in The Journal of the Acoustical Society of America (01-06-2012)“…Franciscana dolphins are small odontocetes hard to study in the field. In particular, little is known on their echolocation behavior in the wild. In this study…”
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Coordinated up-regulation of cyclooxygenase-2 and microsomal prostaglandin E synthase 1 transcription by nuclear factor kappa B and early growth response-1 in macrophages
Published in Cellular signalling (01-10-2010)“…Prostaglandin (PG) E2 is a potent lipid mediator that plays an essential role in inflammation, fever and pain. It is produced from arachidonic acid (AA) by a…”
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Inhibition of Hypoxia Inducible Factor-1α by Dihydroxyphenylethanol, a Product from Olive Oil, Blocks Microsomal Prostaglandin-E Synthase-1/Vascular Endothelial Growth Factor Expression and Reduces Tumor Angiogenesis
Published in Clinical cancer research (15-08-2010)“…Purpose: 2-(3,4-dihydroxyphenil)-ethanol (DPE), a polyphenol present in olive oil, has been found to attenuate the growth of colon cancer cells, an effect…”
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Expression and function of the nuclear factor of activated T cells in colon carcinoma cells: involvement in the regulation of cyclooxygenase-2
Published in The Journal of biological chemistry (11-03-2005)“…Increasing evidence shows a crucial role of the Ca2+/ calcineurin-mediated activation of the nuclear factor of activated T cells (NFAT) in the regulation of a…”
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Nitric Oxide and Electrophilic Cyclopentenone Prostaglandins in Redox signaling, Regulation of Cytoskeleton Dynamics and Intercellular Communication
Published in Frontiers in cell and developmental biology (07-05-2021)“…Nitric oxide (NO) and electrophilic cyclopentenone prostaglandins (CyPG) are local mediators that modulate cellular response to oxidative stress in different…”
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Inhibition of lipopolysaccharide-induced gene expression by liver X receptor ligands in macrophages involves interference with early growth response factor 1
Published in Prostaglandins, leukotrienes and essential fatty acids (01-05-2015)“…Abstract Liver X receptors (LXRs) are nuclear receptors that act as ligand-dependent transcription factors forming permissive heterodimers with retinoid X…”
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Towards understanding the ontogeny of echolocation in franciscana dolphins (Pontoporia blainvillei)
Published in Marine mammal science (01-10-2016)Get full text
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Description and clustering of echolocation signals of Commerson's dolphins (Cephalorhynchus commersonii) in Bahía San Julián, Argentina
Published in The Journal of the Acoustical Society of America (01-10-2015)“…Commerson's dolphins (Cephalorhynchus commersonii) inhabit coastal waters of Southern South America and Kerguelen Islands. Limited information exists about the…”
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Peroxisome-proliferator-activated receptor alpha agonists inhibit cyclo-oxygenase 2 and vascular endothelial growth factor transcriptional activation in human colorectal carcinoma cells via inhibition of activator protein-1
Published in Biochemical journal (01-04-2006)“…Recent evidence indicates that PPAR (peroxisome-proliferator-activated receptor) alpha ligands possess anti-inflammatory and antitumoural properties owing to…”
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Prostanoid signal transduction and gene expression in the endothelium : Role in cardiovascular diseases
Published in Cardiovascular research (01-06-2006)“…Endothelial cells play an active role in the maintenance of homeostasis. Endothelial injury can give rise to endothelial dysfunction in which the profile of…”
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Communication sounds of Commerson's dolphins (Cephalorhynchus commersonii) and contextual use of vocalizations
Published in Marine mammal science (01-10-2016)“…Cetaceans produce a variety of vocalizations to communicate; however, little information exists on the acoustic behavior displayed by Commerson's dolphins…”
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Cyclooxygenase-2 deficiency in macrophages leads to defective p110γ PI3K signaling and impairs cell adhesion and migration
Published in The Journal of immunology (1950) (01-07-2013)“…Cyclooxygenase (Cox)-2 dependent PGs modulate several functions in many pathophysiological processes, including migration of immune cells. In this study, we…”
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The hepatitis B virus X protein promotes tumor cell invasion by inducing membrane-type matrix metalloproteinase-1 and cyclooxygenase-2 expression
Published in The Journal of clinical investigation (01-12-2002)“…Hepatocellular carcinoma is strongly associated with chronic infection by the hepatitis B virus (HBV) and has poor prognosis due to intrahepatic metastasis…”
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Cyclooxygenase-independent inhibitory effects on T cell activation of novel 4,5-dihydro-3 trifluoromethyl pyrazole cyclooxygenase-2 inhibitors
Published in International immunopharmacology (01-10-2010)“…Anti-inflammatory efficacy of non-steroidal anti-inflammatory drugs (NSAIDs) has been related to their properties as inhibitors of cyclooxygenase…”
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Induction of Cyclooxygenase-2 on Activated T Lymphocytes: Regulation of T Cell Activation by Cyclooxygenase-2 Inhibitors
Published in The Journal of immunology (1950) (01-07-1999)“…Cyclooxygenase (COX), known to exist in two isoforms, COX-1 and COX-2, is a key enzyme in prostaglandin synthesis and the target for most nonsteroidal…”
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