Search Results - "Étienne Coyaud"

A proximity-dependent biotinylation map of a human cell by Go, Christopher D., Knight, James D. R., Rajasekharan, Archita, Rathod, Bhavisha, Hesketh, Geoffrey G., Abe, Kento T., Youn, Ji-Young, Samavarchi-Tehrani, Payman, Zhang, Hui, Zhu, Lucie Y., Popiel, Evelyn, Lambert, Jean-Philippe, Coyaud, Étienne, Cheung, Sally W. T., Rajendran, Dushyandi, Wong, Cassandra J., Antonicka, Hana, Pelletier, Laurence, Palazzo, Alexander F., Shoubridge, Eric A., Raught, Brian, Gingras, Anne-Claude

“…Compartmentalization is a defining characteristic of eukaryotic cells, and partitions distinct biochemical processes into discrete subcellular locations…”
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VAPs and ACBD5 tether peroxisomes to the ER for peroxisome maintenance and lipid homeostasis by Hua, Rong, Cheng, Derrick, Coyaud, Étienne, Freeman, Spencer, Di Pietro, Erminia, Wang, Yuqing, Vissa, Adriano, Yip, Christopher M, Fairn, Gregory D, Braverman, Nancy, Brumell, John H, Trimble, William S, Raught, Brian, Kim, Peter K

“…Lipid exchange between the endoplasmic reticulum (ER) and peroxisomes is necessary for the synthesis and catabolism of lipids, the trafficking of cholesterol,…”
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LUZP1 and the tumor suppressor EPLIN modulate actin stability to restrict primary cilia formation by Gonçalves, João, Sharma, Amit, Coyaud, Étienne, Laurent, Estelle M N, Raught, Brian, Pelletier, Laurence

“…Cilia and flagella are microtubule-based cellular projections with important sensory and motility functions. Their absence or malfunction is associated with a…”
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Tankyrase regulates epithelial lumen formation via suppression of Rab11 GEFs by Chandrakumar, Arun A, Coyaud, Étienne, Marshall, Christopher B, Ikura, Mitsuhiko, Raught, Brian, Rottapel, Robert

“…Rab11 GTPase proteins are required for cytokinesis, ciliogenesis, and lumenogenesis. Rab11a is critical for apical delivery of podocalyxin (PODXL) during lumen…”
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Palmitoylation of NOD1 and NOD2 is required for bacterial sensing by Lu, Yan, Zheng, Yuping, Coyaud, Étienne, Zhang, Chao, Selvabaskaran, Apiraam, Yu, Yuyun, Xu, Zizhen, Weng, Xialian, Chen, Ji Shun, Meng, Ying, Warner, Neil, Cheng, Xiawei, Liu, Yangyang, Yao, Bingpeng, Hu, Hu, Xia, Zonping, Muise, Aleixo M, Klip, Amira, Brumell, John H, Girardin, Stephen E, Ying, Songmin, Fairn, Gregory D, Raught, Brian, Sun, Qiming, Neculai, Dante

“…The nucleotide oligomerization domain (NOD)-like receptors 1 and 2 (NOD1/2) are intracellular pattern-recognition proteins that activate immune signaling…”
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The in vivo Interaction Landscape of Histones H3.1 and H3.3 by Siddaway, Robert, Milos, Scott, Coyaud, Étienne, Yun, Hwa Young, Morcos, Shahir M., Pajovic, Sanja, Campos, Eric I., Raught, Brian, Hawkins, Cynthia

“…Chromatin structure, transcription, DNA replication, and repair are regulated via locus-specific incorporation of histone variants and posttranslational…”
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MARK3-mediated phosphorylation of ARHGEF2 couples microtubules to the actin cytoskeleton to establish cell polarity by Sandí, María-José, Marshall, Christopher B, Balan, Marc, Coyaud, Étienne, Zhou, Ming, Monson, Daniel M, Ishiyama, Noboru, Chandrakumar, Arun A, La Rose, José, Couzens, Amber L, Gingras, Anne-Claude, Raught, Brian, Xu, Wei, Ikura, Mitsuhiko, Morrison, Deborah K, Rottapel, Robert

“…The PAR-1-MARK pathway controls cell polarity through the phosphorylation of microtubule-associated proteins. Rho-Rac guanine nucleotide exchange factor 2…”
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The Ion Transporter NKCC1 Links Cell Volume to Cell Mass Regulation by Suppressing mTORC1 by Demian, Wael L., Persaud, Avinash, Jiang, Chong, Coyaud, Étienne, Liu, Shixuan, Kapus, Andras, Kafri, Ran, Raught, Brian, Rotin, Daniela

“…mTORC1 regulates cellular growth and is activated by growth factors and by essential amino acids such as Leu. Leu enters cells via the Leu transporter…”
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A Comprehensive, Flexible Collection of SARS-CoV-2 Coding Regions by Kim, Dae-Kyum, Knapp, Jennifer J, Kuang, Da, Chawla, Aditya, Cassonnet, Patricia, Lee, Hunsang, Sheykhkarimli, Dayag, Samavarchi-Tehrani, Payman, Abdouni, Hala, Rayhan, Ashyad, Li, Roujia, Pogoutse, Oxana, Coyaud, Étienne, van der Werf, Sylvie, Demeret, Caroline, Gingras, Anne-Claude, Taipale, Mikko, Raught, Brian, Jacob, Yves, Roth, Frederick P

“…The world is facing a global pandemic of COVID-19 caused by the SARS-CoV-2 coronavirus. Here we describe a collection of codon-optimized coding sequences for…”
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MAPL loss dysregulates bile and liver metabolism in mice by Goyon, Vanessa, Besse‐Patin, Aurèle, Zunino, Rodolfo, Ignatenko, Olesia, Nguyen, Mai, Coyaud, Étienne, Lee, Jonathan M, Nguyen, Bich N, Raught, Brian, McBride, Heidi M

“…Mitochondrial and peroxisomal anchored protein ligase (MAPL) is a dual ubiquitin and small ubiquitin‐like modifier (SUMO) ligase with roles in mitochondrial…”
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CEP120 and SPICE1 Cooperate with CPAP in Centriole Elongation by Comartin, David, Gupta, Gagan D., Fussner, Eden, Coyaud, Étienne, Hasegan, Monica, Archinti, Marco, Cheung, Sally W.T., Pinchev, Deborah, Lawo, Steffen, Raught, Brian, Bazett-Jones, David P., Lüders, Jens, Pelletier, Laurence

“…Centrosomes organize microtubule (MT) arrays and are comprised of centrioles surrounded by ordered pericentriolar proteins [1–4]. Centrioles are barrel-shaped…”
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The Deubiquitinase USP37 Regulates Chromosome Cohesion and Mitotic Progression by Yeh, Christina, Coyaud, Étienne, Bashkurov, Mikhail, van der Lelij, Petra, Cheung, Sally W.T., Peters, Jan Michael, Raught, Brian, Pelletier, Laurence

“…A bipolar mitotic spindle facilitates the equal segregation of chromosomes to two daughter cells. To achieve bipolar attachment of microtubules to kinetochores…”
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EXD2 governs germ stem cell homeostasis and lifespan by promoting mitoribosome integrity and translation by Silva, Joana, Aivio, Suvi, Knobel, Philip A., Bailey, Laura J., Casali, Andreu, Vinaixa, Maria, Garcia-Cao, Isabel, Coyaud, Étienne, Jourdain, Alexis A., Pérez-Ferreros, Pablo, Rojas, Ana M., Antolin-Fontes, Albert, Samino-Gené, Sara, Raught, Brian, González-Reyes, Acaimo, Ribas de Pouplana, Lluís, Doherty, Aidan J., Yanes, Oscar, Stracker, Travis H.

“…Mitochondria are subcellular organelles that are critical for meeting the bioenergetic and biosynthetic needs of the cell. Mitochondrial function relies on…”
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Differential requirements for Tousled-like kinases 1 and 2 in mammalian development by Segura-Bayona, Sandra, Knobel, Philip A, González-Burón, Helena, Youssef, Sameh A, Peña-Blanco, Aida, Coyaud, Étienne, López-Rovira, Teresa, Rein, Katrin, Palenzuela, Lluís, Colombelli, Julien, Forrow, Stephen, Raught, Brian, Groth, Anja, de Bruin, Alain, Stracker, Travis H

“…The regulation of chromatin structure is critical for a wide range of essential cellular processes. The Tousled-like kinases, TLK1 and TLK2, regulate ASF1, a…”
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CHCHD2 Is Coamplified with EGFR in NSCLC and Regulates Mitochondrial Function and Cell Migration by Wei, Yuhong, Vellanki, Ravi N, Coyaud, Étienne, Ignatchenko, Vladimir, Li, Lei, Krieger, Jonathan R, Taylor, Paul, Tong, Jiefei, Pham, Nhu-An, Liu, Geoffrey, Raught, Brian, Wouters, Bradly G, Kislinger, Thomas, Tsao, Ming Sound, Moran, Michael F

“…Coiled-coil-helix-coiled-coil-helix domain-containing 2, a mitochondrial protein, encoded by CHCHD2 is located at chromosome 7p11.2 and proximal to the EGFR…”
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A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface by Gupta, Gagan D., Coyaud, Étienne, Gonçalves, João, Mojarad, Bahareh A., Liu, Yi, Wu, Qianzhu, Gheiratmand, Ladan, Comartin, David, Tkach, Johnny M., Cheung, Sally W.T., Bashkurov, Mikhail, Hasegan, Monica, Knight, James D., Lin, Zhen-Yuan, Schueler, Markus, Hildebrandt, Friedhelm, Moffat, Jason, Gingras, Anne-Claude, Raught, Brian, Pelletier, Laurence

“…The centrosome is the primary microtubule organizing center of the cells and templates the formation of cilia, thereby operating at a nexus of…”
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The emerging landscape of single-molecule protein sequencing technologies by Alfaro, Javier Antonio, Bohländer, Peggy, Dai, Mingjie, Filius, Mike, Howard, Cecil J., van Kooten, Xander F., Ohayon, Shilo, Pomorski, Adam, Schmid, Sonja, Aksimentiev, Aleksei, Anslyn, Eric V., Bedran, Georges, Cao, Chan, Chinappi, Mauro, Coyaud, Etienne, Dekker, Cees, Dittmar, Gunnar, Drachman, Nicholas, Eelkema, Rienk, Goodlett, David, Hentz, Sébastien, Kalathiya, Umesh, Kelleher, Neil L., Kelly, Ryan T., Kelman, Zvi, Kim, Sung Hyun, Kuster, Bernhard, Rodriguez-Larrea, David, Lindsay, Stuart, Maglia, Giovanni, Marcotte, Edward M., Marino, John P., Masselon, Christophe, Mayer, Michael, Samaras, Patroklos, Sarthak, Kumar, Sepiashvili, Lusia, Stein, Derek, Wanunu, Meni, Wilhelm, Mathias, Yin, Peng, Meller, Amit, Joo, Chirlmin

“…Single-cell profiling methods have had a profound impact on the understanding of cellular heterogeneity. While genomes and transcriptomes can be explored at…”
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USP7 Regulates Cytokinesis through FBXO38 and KIF20B by Georges, Anna, Coyaud, Etienne, Marcon, Edyta, Greenblatt, Jack, Raught, Brian, Frappier, Lori

“…The ubiquitin specific protease 7 (USP7 or HAUSP) is known to regulate a variety of cellular processes by binding and deubiquitylating specific target…”
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Haploinsufficiency of RREB1 causes a Noonan-like RASopathy via epigenetic reprogramming of RAS-MAPK pathway genes by Kent, Oliver A., Saha, Manipa, Coyaud, Etienne, Burston, Helen E., Law, Napoleon, Dadson, Keith, Chen, Sujun, Laurent, Estelle M., St-Germain, Jonathan, Sun, Ren X., Matsumoto, Yoshinori, Cowen, Justin, Montgomery-Song, Aaryn, Brown, Kevin R., Ishak, Charles, Rose, Jose La, De Carvalho, Daniel D., He, Housheng Hansen, Raught, Brian, Billia, Filio, Kannu, Peter, Rottapel, Robert

“…RAS-MAPK signaling mediates processes critical to normal development including cell proliferation, survival, and differentiation. Germline mutation of RAS-MAPK…”
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Salmonella effector SopD promotes plasma membrane scission by inhibiting Rab10 by Boddy, Kirsten C., Zhu, Hongxian, D’Costa, Vanessa M., Xu, Caishuang, Beyrakhova, Ksenia, Cygler, Miroslaw, Grinstein, Sergio, Coyaud, Etienne, Laurent, Estelle M. N., St-Germain, Jonathan, Raught, Brian, Brumell, John H.

“…Salmonella utilizes translocated virulence proteins (termed effectors) to promote host cell invasion. The effector SopD contributes to invasion by promoting…”
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