Search Results - "Çetin Atalay, R"

P0449 : Non steroidal anti inflammatory drugs in liver fibrosis by Akhan, E, Oğ uz, O, Çetin, E, Çetin Atalay, R

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MDeePred: novel multi-channel protein featurization for deep learning-based binding affinity prediction in drug discovery by Rifaioglu, A S, Cetin Atalay, R, Cansen Kahraman, D, Doğan, T, Martin, M, Atalay, V

“…Abstract Motivation Identification of interactions between bioactive small molecules and target proteins is crucial for novel drug discovery, drug repurposing…”
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An ontology for collaborative construction and analysis of cellular pathways by Demir, E., Babur, O., Dogrusoz, U., Gursoy, A., Ayaz, A., Gulesir, G., Nisanci, G., Cetin-Atalay, R.

“…Motivation: As the scientific curiosity in genome studies shifts toward identification of functions of the genomes in large scale, data produced about cellular…”
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P0402 : Combination therapy for hepatocellular carcinoma: A systems biology perspective on the synergistic antitumor activity of sorafenib with PI3K/AKT pathway inhibitors by Ersahin, T, Tuncbag, N, Acar, A, Cetin-Atalay, R

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PATIKA: an integrated visual environment for collaborative construction and analysis of cellular pathways by DEMIR, E, BABUR, O, DOGRUSOZ, U, GURSOY, A, NISANCI, G, CETIN-ATALAV, R, OZTURK, M

“…Availability of the sequences of entire genomes shifts the scientific curiosity towards the identification of function of the genomes in large scale as in…”
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Cytotoxic activities of some novel benzhydrylpiperazine derivatives by Gurdal, E E, Yarim, M, Durmaz, I, Cetin-Atalay, R

“…This study presents the synthesis of nineteen 1-(substitutedbenzoyl)-4-benzhydrylpiperazine and 1-[(substitutedphenyl)sulfonyl]-4-benzhydrylpiperazine…”
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Implicit motif distribution based hybrid computational kernel for sequence classification by Atalay, Volkan, Cetin-Atalay, Rengul

“…Motivation: We designed a general computational kernel for classification problems that require specific motif extraction and search from sequences. Instead of…”
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Gene mutations involved in drug resistance in liver cancer cells using a new rna-seq data analysis workflow by Akhan Guzelcan, E., Shojaei, M., Acar, A.C., Cetin Atalay, R.

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Attributed Relational Graphs for Cell Nucleus Segmentation in Fluorescence Microscopy Images by Arslan, S., Ersahin, T., Cetin-Atalay, R., Gunduz-Demir, C.

“…More rapid and accurate high-throughput screening in molecular cellular biology research has become possible with the development of automated microscopy…”
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601 - Bioactivities of novel boehmeriasin derivatives in liver cancer cells by Guzelcan, E. Akhan, Baumann, M., Baxendale, I., Atalay, R. Cetin

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Patika: an integrated visual environmentfor collaborative construction and analysis of cellularpathways by Demir, E., Babur, O., Dogrusoz, U., Gursoy, A., Nisanci, G., Cetin-Atalay, R., Ozturk, M.

“…Motivation: Availability of the sequences of entire genomes shifts the scientific curiosity towards the identification of function of the genomes in large…”
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Molecular characterization of a full genome Turkish hepatitis C virus 1b isolate (HCV-TR1): a predominant viral form in Turkey by Yildiz, Esra, Oztan, Asli, Sar, Funda, Pinarbasi, Ergun, Cetin-Atalay, Rengul, Akkiz, Hikmet, Ozturk, Mehmet

“…Based on direct sequencing information from 5'UTR and NS5B regions, we identified subtype lb as a predominant hepatitis C virus genome in Turkey, which…”
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Bioactivities of novel boehmeriasin derivatives in liver cancer cells by Guzelcan, E. Akhan, Baumann, M, Baxendale, I, Atalay, R. Cetin

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Synthesis and Cytotoxic Activity of Novel 3-methyl-1-[(4-substitutedpiperazin-1-yl)methyl]-1H-indole Derivatives by Koksal, M., Yarim, M., Durmaz, I., Cetin-Atalay, R.

“…Abstract A series of novel 3-methyl-1-[(4-substitutedpiperazin-1-yl)methyl]-1 H -indoles ( 3a–l) were synthesized and their cytotoxicities were analyzed…”
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Quinoides and VEGFR2 TKIs influence the fate of hepatocellular carcinoma and its cancer stem cells by Kahraman, Deniz Cansen, Hanquet, Gilles, Jeanmart, Loïc, Lanners, Steve, Šramel, Peter, Boháč, Andrej, Cetin-Atalay, Rengul

“…Bioactivities of quinoides and VEGFR2 TKIs in hepatocellular cancer (HCC) and cancer stem cells (HCSCs) were studied. The compounds exhibited IC values in μM…”
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Acquired tolerance of hepatocellular carcinoma cells to selenium deficiency: A selective survival mechanism? by IRMAK, Meliha Burcu, INCE, Gulayse, OZTURK, Mehmet, CETIN-ATALAY, Rengul

“…Selenium is essential to human health, and its deficiency is associated with different diseases including liver necrosis. Selenium is protective against viral…”
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Reprogramming of Replicative Senescence in Hepatocellular Carcinoma-Derived Cells by Ozturk, Nuri, Erdal, Esra, Mumcuoglu, Mine, Akcali, Kamil C., Yalcin, Ozden, Senturk, Serif, Arslan-Ergul, Ayca, Gur, Bala, Yulug, Isik, Cetin-Atalay, Rengul, Yakicier, Cengiz, Yagci, Tamer, Tez, Mesut, Ozturk, Mehmet

“…Tumor cells have the capacity to proliferate indefinitely that is qualified as replicative immortality. This ability contrasts with the intrinsic control of…”
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Microscopic image classification via ℂWT-based covariance descriptors using Kullback-Leibler distance by Keskin, F., Cetin, A. E., Ersahin, T., Cetin-Atalay, R.

“…In this paper, we present a novel method for classification of cancer cell line images using complex wavelet-based region covariance matrix descriptors…”
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Identification of relative protein bands in polyacrylamide gel electrophoresis (PAGE) using multiresolution snake algorithm by Gurcan, M.N., Koyuturk, M., Yildiz, H.S., Cetin-Atalay, R., Cetin, A.N.

“…Polyacrylamide gel electrophoresis (PAGE) is one of the most widely used techniques in protein research. In the protein purification process, it is important…”
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p53 mutations as fingerprints of environmental carcinogens by Cetin-Atalay, Rengul, Ozturk, Mehmet

“…Mutations of the p53 tumor suppressor gene occur in a great majority of human cancers. The protein product of p53 gene is involved in DNA damage response…”
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