Search Results - "Çapan, Y"

pH-sensitive chitosan-PEG-decorated hollow mesoporous silica nanoparticles could be an effective treatment for acute myeloid leukemia (AML) by Ultav, G., Tonbul, H., Tavukcuoglu, E., Ozturk, S. C., Akbas, S., Sahin, A., Esendagli, G., Capan, Y.

“…Improved treatment of acute myeloid leukemia (AML) could be possible by longer retention of anticancer drugs in the bloodstream. In this study, it was aimed to…”
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Simultaneous Determination of Dexpanthenol, Lidocaine Hydrochloride, Mepyramine Maleate and their Related Substances by a RP-HPLC Method in Topical Dosage Forms by Doganay, A, Koksel, B, Gundogdu, S O, Capan, Y

“…Abstract The pharmaceutical combination of dexpanthenol (DPA), lidocaine hydrochloride (LIH) and mepyramine maleate (MAM) is used for their anti-allergic,…”
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Microbiological and clinical comparison of chlorhexidine buccoadhesive tablet and chlorhexidine mouthrinse by Aktaş, A., Giray, B., Çapan, Y., Menemenlioğlu, D., Hayran, M., İkinci, G., Vural, İ.

“…Chlorhexidine, which is a gold standard for antiplaque agents, was prepared as a buccoadhesive controlled-release drug formulation. The released amount and…”
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Histological and bioadhesion studies on buccal bioadhesive tablets containing a penetration enhancer sodium glycodeoxycholate by Şenel, S, Çapan, Y, Sargon, M.F, Giray, C.B, Hıncal, A.A

“…For many drugs, buccal route offers many advantages over conventional routes of delivery with an improved bioavailability due to the avoidance of degradation…”
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Characterization of bevacizumab by dynamic light scattering while maintaining its native structure by Akbas, S, Sahin, A, Calis, S, Oncel, H, Capan, Y

“…Bevacizumab, is a humanized monoclonal antibody and patents on Avastin® (Bevacizumab, Roche) will expire in the US in 2019 and in Europe in 2022. Therefore,…”
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In vitro studies on enhancing effect of sodium glycocholate on transbuccal permeation of morphine hydrochloride by Şenel, S, Duchêne, D, Hıncal, A.A, Çapan, Y, Ponchel, G

“…During the perioperative period, gastric emptying rate and first-pass metabolism limit the use of peroral morphine. Buccal mucosa appears to be a potential…”
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Counterfeit/Copy Drugs: Patients Safety in the Heart by Capan, Y.

“…Some studies demonstrate that a large proportion of copy drugs contain lower levels of active substances and higher impurity levels than reference drugs. The…”
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An aquaporin 4 antisense oligonucleotide loaded, brain targeted nanoparticulate system design by Kozlu, S, Caban, S, Yerlikaya, F, Fernandez-Megia, E, Novoa-Carballal, R, Riguera, R, Yemisci, M, Gursoy-Ozdemir, Y, Dalkara, T, Couvreur, P, Capan, Y

“…Aquaporins (AQPs), members of the water-channel protein family, are highly expressed in brain tissue especially in astrocytic end-feet. They are important…”
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Effect of polymorphism on in vitro-in vivo properties of carbamazepine conventional tablets by Elqidra, R., Ünlü, N., Çapan, Y., Sahin, G., Dalkara, T., Hincal, A.A.

“…The objective of the present study was to investigate the effect of polymorphism on in vitro-in vivo properties of carbamazepine (CBZ). For this purpose, three…”
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In vitro cytotoxicity of mitoxantrone-incorporated albumin microspheres on acute promyelocytic leukaemia cells by Bozda, S., Çapan, Y., Vural, ., Dalkara, T., Dogan, A. L., Guc, D., H ncal, A. A., Deluca, P. P.

“…In the present study, the preparation and characterization of bovine serum albumin (BSA) microspheres and the evaluation of the in vitro cytotoxicity of these…”
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Enhancement of transbuccal permeation of morphine sulfate by sodium glycodeoxycholate in vitro by Şenel, S., Çapan, Y., Sargon, M.F., İkinci, G., Şolpan, D., Güven, O., Boddé, H.E., Hincal, A.A.

“…In this study, enhancement of transbuccal permeation of morphine sulfate was studied in the presence of sodium glycodeoxycholate (GDC). The permeability of the…”
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Formulation and evaluation of clozapine orally disintegrating tablets prepared by direct compression by Olmez, S S, Vural, I, Sahin, S, Ertugrul, A, Capan, Y

“…In this study, clozapine orally disintegrating tablets (ODTs) were prepared by direct compression method. Disintegration time, resistance to crushing of…”
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The influence of technological parameters on the physicochemical properties of blank PLGA nanoparticles by Ozturk, K, Caban, S, Kozlu, S, Kadayifci, E, Yerlikaya, F, Capan, Y

“…In this work, PLGA nanoparticles were prepared by an emulsification-diffusion technique. The main objective was to optimize the preparation of formulations by…”
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Comparative in vitro studies on PBN loaded nanoparticles prepared by biodegradable chitosan, PLGA polymers and their PEGylated block copolymers by Ozturk, K., Fernandez-Megia, E., Novoa-Carballal, R., Riguera, R., Yemisci, M., Gursoy-Ozdemir, Y., Dalkara, T., Couvreur, P., Capan, Y.

“…α-phenyl-N-tert-butyl nitrone (PBN) is a neuroprotective free radical scavenger however it has low in vivo stability and blood residence time. Aim. of this…”
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Comparative evaluation of in vitro parameters of tamoxifen citrate loaded poly(lactide-co-glycolide), poly(epsilon-caprolactone) and chitosan nanoparticles by Cirpanli, Y, Yerlikaya, F, Ozturk, K, Erdogar, N, Launay, M, Gegu, C, Leturgez, T, Bilensoy, E, Calis, S, Capan, Y

“…Tamoxifen (TAM), the clinical choice for the antiestrogen treatment of advanced or metastatic breast cancer, was formulated in nanoparticulate carrier systems…”
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Preparation and evaluation of alpha-phenyl-n-tert-butyl nitrone (PBN)-encapsulated chitosan and PEGylated chitosan nanoparticles by Pinarbasli, O, Aktas, Y, Dalkara, T, Andrieux, K, Alonso, M J, Fernandez-Megia, E, Novoa-Carballal, R, Riguera, R, Couvreur, P, Capan, Y

“…Alpha-phenyl-n-tert-butyl nitrone (PBN) shows its major effect by scavenging free radicals formed in the ischemia and it has the ability to penetrate through…”
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Preparation and characterization of PLGA nanospheres for the targeted delivery of NR2B-specific antisense oligonucleotides to the NMDA receptors in the brain by Kilic, A. C., Capan, Y., Vural, I., Gursoy, R. N., Dalkara, T., Cuine, A., Hincal, A. A.

“…Treatment of central nervous system (CNS) diseases with potentially useful pharmaceuticals is prevented by the blood-brain barrier (BBB). The BBB is a unique…”
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Formulation and in vitro-in vivo evaluation of buccoadhesive morphine sulfate tablets by ANLAR, S, CAPAN, Y, GÜVEN, O, GÖGÜS, A, DALKARA, T, HINCAL, A. A

“…Buccoadhesive controlled-release systems for the delivery of morphine sulfate were prepared by compression of hydroxypropyl methylcellulose (HPMC) with…”
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In vitro/in vivo studies on a buccal bioadhesive tablet formulation of carbamazepine by Ikinci, G, Capan, Y, Senel, S, Alaaddinoğlu, E, Dalkara, T, Hincal, A A

“…A buccoadhesive controlled-release system for delivery of carbamazepine (CBZ) was prepared by compression of hydroxypropyl methylcellulose (HPMC) and carbomer,…”
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Development and evaluation of paclitaxel nanoparticles using a quality-by-design approach by Yerlikaya, Firat, Ozgen, Aysegul, Vural, Imran, Guven, Olgun, Karaagaoglu, Ergun, Khan, Mansoor A, Capan, Yilmaz

“…The aims of this study were to develop and characterize paclitaxel nanoparticles, to identify and control critical sources of variability in the process, and…”
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