Retinoblastoma-Like Tumor with Brain Metastasis in a Border Collie

In this report, we described the clinical, ultrasound, contrast-enhanced T2-weighted brain magnetic resonance imaging (MRI), and histopathological findings of a retinoblastoma-like tumor with brain metastasis in a 3-year-old male Border Collie. Ophthalmoscopic and ultrasonographic examination reveal...

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Bibliographic Details
Published in:	Veteriner fakultesi dergisi Vol. 30; no. 3; pp. 401 - 405
Main Authors:	ÖZGENCİL, F. Eser, ÇERKEZ, E. Esma, YAZAN, Ece, DİKBAŞ TSATSARONIS, Nihan, KULEYİNOĞLU, Özgecan, ÇAĞLAR, Volkan, ÖZDEMİR, Dilek, GÖKÇE, A. Perran, GÜREL, Aydın, ÜLGENALP, Onur
Format:	Journal Article
Language:	English
Published:	Kafkas University, Faculty of Veterinary Medicine 2024
Subjects:	dog embryonal tumors with multilayered rosettes (etmr) ocular neoplasia primary neuroectodermal tumors (pnet) retinoblastoma-like tumor
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Summary:	In this report, we described the clinical, ultrasound, contrast-enhanced T2-weighted brain magnetic resonance imaging (MRI), and histopathological findings of a retinoblastoma-like tumor with brain metastasis in a 3-year-old male Border Collie. Ophthalmoscopic and ultrasonographic examination revealed leukocoria associated with a solid mass of retinal origin in the left eye. Simultaneous contrast-enhanced T2- weighted brain MRI evaluation revealed solid masses at three different locations: the first one at the levels of the suprasellar cistern, third ventricle and chiasma opticum; the second one in the medulla oblongata adjacent to the caudal cranial fossa; and the third one in the left intraocular region. Histopathological examination of the extracted mass in the globe revealed a retinoblastoma-like tumor. The patient died before receiving radiotherapy treatment. In conclusion: this report highlights the importance of early diagnosis through ophthalmoscopic and ultrasonographic examinations. Emphasizing the brain as a potential secondary metastatic site, the report underscores the critical need to create a window for timely radiotherapy. Furthermore, the recommendation is made to evaluate dogs with leukocoria during ophthalmoscopic examination for both retinoblastoma and potential brain metastasis.
ISSN:	1300-6045 1309-2251
DOI:	10.9775/kvfd.2023.31363