Search Results - "Åslund, Andreas K.O."
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Effect of Ultrasound on the Vasculature and Extravasation of Nanoscale Particles Imaged in Real Time
Published in Ultrasound in medicine & biology (01-11-2019)“…AbstractUltrasound and microbubbles have been found to improve the delivery of drugs and nanoparticles to tumor tissue. To obtain new knowledge on the…”
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Delivering the power of nanomedicine to patients today
Published in Journal of controlled release (10-10-2020)“…The situation of the COVID-19 pandemic reminds us that we permanently need high-value flexible solutions to urgent clinical needs including simplified…”
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Nanoparticle delivery to the brain — By focused ultrasound and self-assembled nanoparticle-stabilized microbubbles
Published in Journal of controlled release (28-12-2015)“…The blood–brain barrier (BBB) constitutes a significant obstacle for the delivery of drugs into the central nervous system (CNS). Nanoparticles have been able…”
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The effect of poly(ethylene glycol) coating and monomer type on poly(alkyl cyanoacrylate) nanoparticle interactions with lipid monolayers and cells
Published in Colloids and surfaces, B, Biointerfaces (01-02-2017)“…[Display omitted] •Type of PEG coating on PACA nanoparticles affects interaction with lipid monolayers.•It also affects PACA nanoparticle association with and…”
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Efficient Enhancement of Blood-Brain Barrier Permeability Using Acoustic Cluster Therapy (ACT)
Published in Theranostics (2017)“…The blood-brain barrier (BBB) is a major obstacle in drug delivery for diseases of the brain, and today there is no standardized route to surpass it. One…”
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Identification of novel cyanoacrylate monomers for use in nanoparticle drug delivery systems prepared by miniemulsion polymerisation – A multistep screening approach
Published in International journal of pharmaceutics: X (01-12-2022)“…Poly (alkyl cyanoacrylate) (PACA) polymeric nanoparticles (NPs) are promising drug carriers in drug delivery. However, the selection of commercially available…”
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Two-Photon Fluorescence and Magnetic Resonance Specific Imaging of Aβ Amyloid Using Hybrid Nano-GdF3 Contrast Media
Published in ACS applied bio materials (20-08-2018)“…Real time in vivo detection of Amyloid β (Aβ) deposits at an early stage may lead to faster and more conclusive diagnosis of Alzheimer’s disease (AD) and can…”
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Preclinical Efficacy of Cabazitaxel Loaded Poly(2-alkyl cyanoacrylate) Nanoparticle Variants
Published in International journal of nanomedicine (01-01-2024)“…Biodegradable poly(alkyl cyanoacrylate) (PACA) nanoparticles (NPs) are receiving increasing attention in anti-cancer nanomedicine development not only for…”
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Nanoparticle-loaded microbubbles for treatment of lung cancer
Published in European journal of pharmaceutical sciences (01-08-2024)“…Lung cancer is one of the most common cancers and a leading cause of death, with poor prognosis and high unmet clinical need. Chemotherapy is a common part of…”
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Intraperitoneal administration of cabazitaxel-loaded nanoparticles in peritoneal metastasis models
Published in Nanomedicine (01-02-2023)“…Colorectal and ovarian cancers frequently develop peritoneal metastases with few treatment options. Intraperitoneal chemotherapy has shown promising…”
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Ultrasound-mediated delivery and distribution of polymeric nanoparticles in the normal brain parenchyma of a metastatic brain tumour model
Published in PloS one (16-01-2018)“…The treatment of brain diseases is hindered by the blood-brain barrier (BBB) preventing most drugs from entering the brain. Focused ultrasound (FUS) with…”
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Labeling nanoparticles: Dye leakage and altered cellular uptake
Published in Cytometry. Part A (01-08-2017)“…In vitro and in vivo behavior of nanoparticles (NPs) is often studied by tracing the NPs with fluorescent dyes. This requires stable incorporation of dyes…”
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Cellular uptake and intracellular degradation of poly(alkyl cyanoacrylate) nanoparticles
Published in Journal of nanobiotechnology (08-01-2016)“…Poly(alkyl cyanoacrylate) (PACA) nanoparticles have shown promise as drug carriers both to solid tumors and across the blood-brain barrier. Efficient drug…”
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Contrast Enhanced Magnetic Resonance Imaging of Amyloid-β Plaques in a Murine Alzheimer's Disease Model
Published in Journal of Alzheimer's disease (01-01-2023)“…Early detection of amyloid-β (Aβ) aggregates is a critical step to improve the treatment of Alzheimer's disease (AD) because neuronal damage by the Aβ…”
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A comparative biodistribution study of polymeric and lipid-based nanoparticles
Published in Drug delivery and translational research (01-09-2022)“…Biodistribution of nanoencapsulated bioactive compounds is primarily determined by the size, shape, chemical composition and surface properties of the…”
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Gelling kinetics and in situ mineralization of alginate hydrogels: A correlative spatiotemporal characterization toolbox
Published in Acta biomaterialia (15-10-2016)“…[Display omitted] Due to their large water content and structural similarities to the extracellular matrix, hydrogels are an attractive class of material in…”
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Simple and Robust Intravital Microscopy Procedures in Hybrid TIE2GFP-BALB/c Transgenic Mice
Published in Molecular imaging and biology (01-06-2020)“…Purpose The endeavor of deciphering intricate phenomena within the field of molecular medicine dictates the necessity to investigate tumor/disease…”
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Therapeutic Effect of Cabazitaxel and Blood-Brain Barrier opening in a Patient-Derived Glioblastoma Model
Published in Nanotheranostics (Sydney, NSW) (2019)“…Treatment of glioblastoma and other diseases in the brain is especially challenging due to the blood-brain barrier, which effectively protects the brain…”
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Quantification and Qualitative Effects of Different PEGylations on Poly(butyl cyanoacrylate) Nanoparticles
Published in Molecular pharmaceutics (07-08-2017)“…Protein adsorption on nanoparticles (NPs) used in nanomedicine leads to opsonization and activation of the complement system in blood, which substantially…”
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Nanoparticle-stabilized microbubbles for multimodal imaging and drug delivery
Published in Contrast media and molecular imaging (01-09-2015)“…Microbubbles (MBs) are routinely used as contrast agents for ultrasound imaging. The use of ultrasound in combination with MBs has also attracted attention as…”
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