Search Results - "Ávila‐López, Pedro A."

Structure‐Based Virtual Screening and in vitro and in vivo Analyses Revealed Potent Methyltransferase G9a Inhibitors as Prospective Anti‐Alzheimer's Agents by Bellver‐Sanchis, Aina, Singh Choudhary, Bhanwar, Companys‐Alemany, Júlia, Sukanya, Ávila‐López, Pedro A., Martínez Rodríguez, Antón Leandro, Brea Floriani, Jose Manuel, Malik, Ruchi, Pallàs, Mercè, Pérez, Belén, Griñán‐Ferré, Christian

“…G9a is a lysine methyltransferase able to di‐methylate lysine 9 of histone H3, promoting the repression of genes involved in learning and memory. Novel…”
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Neuroprotective effects of G9a inhibition through modulation of peroxisome-proliferator activator receptor gamma-dependent pathways by miR-128 by Bellver-Sanchis, Aina, Ávila-López, Pedro A, Tic, Iva, Valle-García, David, Ribalta-Vilella, Marta, Labrador, Luis, Banerjee, Deb Ranjan, Guerrero, Ana, Casadesus, Gemma, Poulard, Coralie, Pallàs, Mercè, Griñán-Ferré, Christian

“…JOURNAL/nrgr/04.03/01300535-202419110-00033/figure1/v/2024-03-08T184507Z/r/image-tiff Dysregulation of G9a, a histone-lysine N-methyltransferase, has been…”
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G9a Inhibition Promotes Neuroprotection through GMFB Regulation in Alzheimer's Disease by Bellver-Sanchis, Aina, Geng, Qizhi, Navarro, Gemma, Ávila-López, Pedro A, Companys-Alemany, Júlia, Marsal-García, Laura, Larramona-Arcas, Raquel, Miró, Lluisa, Perez-Bosque, Anna, Ortuño-Sahagún, Daniel, Banerjee, Deb Ranjan, Choudhary, Bhanwar Singh, Soriano, Francesc X, Poulard, Coralie, Pallàs, Mercè, Du, Hai-Ning, Griñán-Ferré, Christian

“…Epigenetic alterations are a fundamental pathological hallmark of Alzheimer's disease (AD). Herein, we show the upregulation of G9a and H3K9me2 in the brains…”
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Comprehensive bioinformatic analysis reveals oncogenic role of H2A.Z isoforms in cervical cancer progression by Salmerón-Bárcenas, Eric G, Zacapala-Gómez, Ana E, Lozano-Amado, Daniela, Castro-Muñoz, Leonardo J, Leyva-Vázquez, Marco A, Manzo-Merino, Joaquín, Ávila-López, Pedro A

“…Cervical cancer ranks as the fourth most common neoplasia in women worldwide in which epigenetic alterations play an important role. Several studies have…”
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Comprehensive bioinformatic analysis reveals oncogenic role of H2A.Z isoforms in cervical cancer progression by Salmerón-Bárcenas, Eric G, Zacapala-Gómez, Ana E, Lozano-Amado, Daniela, Castro-Muñoz, Leonardo J, Leyva-Vázquez, Marco A, Manzo-Merino, Joaquín, Ávila-López, Pedro A

“…ObjectivesCervical cancer ranks as the fourth most common neoplasia in women worldwide in which epigenetic alterations play an important role. Several studies…”
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PfAP2Tel, harbouring a non‐canonical DNA‐binding AP2 domain, binds to Plasmodium falciparum telomeres by Sierra‐Miranda, Miguel, Vembar, Shruthi‐Sridhar, Delgadillo, Dulce María, Ávila‐López, Pedro A., Herrera‐Solorio, Abril‐Marcela, Lozano Amado, Daniela, Vargas, Miguel, Hernandez‐Rivas, Rosaura

“…Summary The telomeres of the malaria parasite Plasmodium falciparum are essential not only for chromosome end maintenance during blood stage development in…”
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Interplay Between the Histone Variant H2A.Z and the Epigenome in Pancreatic Cancer by Ávila-López, Pedro A, Nuñez-Martínez, Hober N, Peralta-Alvarez, Carlos A, Martinez-Calvillo, Santiago, Recillas-Targa, Félix, Hernández-Rivas, Rosaura

“…The oncogenic process is orchestrated by a complex network of chromatin remodeling elements that shape the cancer epigenome. Histone variant H2A.Z regulates…”
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Integrated bioinformatics analysis reveals that EZH2-rich domains promote transcriptional repression in cervical cancer by Salmerón-Bárcenas, Eric G, Zacapala-Gómez, Ana Elvira, Ortiz-Ortiz, Julio, Torres-Rojas, Francisco I, Ávila-López, Pedro A

“…Cervical cancer is the third female cancer most common worldwide. The carcinogenic process involves an alteration of the mechanisms associated with…”
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Pf AP2Tel, harbouring a non-canonical DNA-binding AP2 domain, binds to Plasmodium falciparum telomeres by Sierra-Miranda, Miguel, Vembar, Shruthi-Sridhar, Delgadillo, Dulce María, Ávila-López, Pedro A., Herrera-Solorio, Abril-Marcela, Lozano Amado, Daniela, Vargas, Miguel, Hernandez-Rivas, Rosaura

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