Search Results - "Ávila, Daiana S"
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Insights into the differential toxicological and antioxidant effects of 4-phenylchalcogenil-7-chloroquinolines in Caenorhabditis elegans
Published in Free radical biology & medicine (01-09-2017)“…Organic selenium and tellurium compounds are known for their broad-spectrum effects in a variety of experimental disease models. However, these compounds…”
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2
MeHg exposure impairs both the catecholaminergic and cholinergic systems resulting in motor and non-motor behavioral changes in Drosophila melanogaster
Published in Chemico-biological interactions (25-09-2022)“…Human exposure to the natural environmental contaminant methylmercury (MeHg) has been associated to adverse health effects. Importantly, the mechanisms by…”
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3
Organoselenotriazoles attenuate oxidative damage induced by mitochondrial dysfunction in mev-1 Caenorhabditis elegans mutants
Published in Journal of trace elements in medicine and biology (01-05-2019)“…Organic selenium compounds have several pharmacological activities already described, as anti-inflammatory and antitumor activities, which have been attributed…”
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4
Nanomaterials in the Environment: Perspectives on in Vivo Terrestrial Toxicity Testing
Published in Frontiers in environmental science (27-10-2017)“…Over the last decade, engineered nanomaterials (NMs) brought a revolutionary development in many sectors of human life including electronics, paints, textiles,…”
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5
Are delta-aminolevulinate dehydratase inhibition and metal concentrations additional factors for the age-related cognitive decline?
Published in International journal of environmental research and public health (17-10-2014)“…Aging is often accompanied by cognitive impairments and influenced by oxidative status and chemical imbalances. Thus, this study was conducted to examine…”
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6
"Manganese-induced neurotoxicity: a review of its behavioral consequences and neuroprotective strategies"
Published in BMC pharmacology & toxicology (04-11-2016)“…Manganese (Mn) is an essential heavy metal. However, Mn's nutritional aspects are paralleled by its role as a neurotoxicant upon excessive exposure. In this…”
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7
The influence of Bauhinia forficata Link subsp. pruinosa tea on lipid peroxidation and non-protein SH groups in human erythrocytes exposed to high glucose concentrations
Published in Journal of ethnopharmacology (21-06-2013)“…Bauhinia forficata (BF) has been traditionally used as tea in folk medicine of Brazil for treatment of Diabetes mellitus (DM). To evaluate the effects of BF…”
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Thimerosal inhibits Drosophila melanogaster tyrosine hydroxylase (DmTyrH) leading to changes in dopamine levels and impaired motor behavior: implications for neurotoxicity
Published in Metallomics (20-02-2019)“…Thimerosal (THIM) is a well-established antifungal and antiseptic agent widely used as a preservative in vaccines. Recent studies identified the neurotoxic…”
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9
Ilex paraguariensis Extract Increases Lifespan and Protects Against the Toxic Effects Caused by Paraquat in Caenorhabditis elegans
Published in International journal of environmental research and public health (26-09-2014)“…Recent studies have shown that phenolic compounds present in yerba mate have antioxidant defense properties. To verify whether Ilex paraguariensis extracts are…”
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10
Synthesis of enantiomerically pure glycerol derivatives containing an organochalcogen unit: In vitro and in vivo antioxidant activity
Published in Arabian journal of chemistry (01-01-2020)“…[Display omitted] We describe here the synthesis of enantiomerically pure chalcogenoethers obtained through the reaction of nucleophilic species of chalcogen…”
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11
A Possible Neuroprotective Action of a Vinylic Telluride against Mn-Induced Neurotoxicity
Published in Toxicological sciences (01-05-2010)“…Manganese (Mn) is a metal required by biological systems. However, environmental or occupational exposure to high levels of Mn can produce a neurological…”
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12
Caenorhabditis elegans as an alternative in vivo model to determine oral uptake, nanotoxicity, and efficacy of melatonin-loaded lipid-core nanocapsules on paraquat damage
Published in International journal of nanomedicine (01-01-2015)“…Caenorhabditis elegans is an alternative in vivo model that is being successfully used to assess the pharmacological and toxic effects of drugs. The…”
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13
Comparative Studies on Dicholesteroyl Diselenide and Diphenyl Diselenide as Antioxidant Agents and their Effect on the Activities of Na+/K+ ATPase and δ-Aminolevulinic acid Dehydratase in the Rat Brain
Published in Neurochemical research (2008)“…The present study sought to evaluate the effect of a newly synthesized selenium compound, dicholesteroyl diselenide (DCDS) and diphenyl diselenide (DPDS) on…”
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14
Mechanisms and Disease Pathogenesis Underlying Metal-Induced Oxidative Stress
Published in Oxidative medicine and cellular longevity (01-01-2018)“…Excess intracellular RONS eventually disrupts the intracellular redox state and energy production resulting in oxidative stress, which manifests itself in the…”
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15
Neem oil based nanopesticide as an environmentally-friendly formulation for applications in sustainable agriculture: An ecotoxicological perspective
Published in The Science of the total environment (10-08-2019)“…Sustainable agriculture encourages practices that present low risks to the environment and human health. To this end, zein (corn protein) can be used to…”
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Reversible reprotoxic effects of manganese through DAF-16 transcription factor activation and vitellogenin downregulation in Caenorhabditis elegans
Published in Life sciences (1973) (15-04-2016)“…Vitellogenesis is the yolk production process which provides the essential nutrients for the developing embryos. Yolk is a lipoprotein particle that presents…”
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17
Metabolic effects of manganese in the nematode Caenorhabditis elegans through DAergic pathway and transcription factors activation
Published in Neurotoxicology (Park Forest South) (01-07-2018)“…•Mn increased fat storage in Caenorhabditis elegans.•The oxygen consumption was decreased by Mn.•Mn did not caused death in dopaminergic neurons in L4 larval…”
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Seleno- and Telluro-xylofuranosides attenuate Mn-induced toxicity in C. elegans via the DAF-16/FOXO pathway
Published in Food and chemical toxicology (01-02-2014)“…•Se- and Te-xylofuranosides depicted low toxicity in C. elegans.•The compounds protected from toxicity-induced by Mn.•Se- and Te-xylofuranosides increased the…”
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Gene–environment interactions: Neurodegeneration in non-mammals and mammals
Published in Neurotoxicology (Park Forest South) (01-09-2010)“…The understanding of how environmental exposures interact with genetics in central nervous system dysfunction has gained great momentum in the last decade…”
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Journal Article Conference Proceeding -
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Thimerosal inhibits Drosophila melanogaster tyrosine hydroxylase (DmTyrH) leading to changes in dopamine levels and impaired motor behavior: implications for neurotoxicityElectronic supplementary information (ESI) available. See DOI: 10.1039/c8mt00268a
Published 20-02-2019“…Thimerosal (THIM) is a well-established antifungal and antiseptic agent widely used as a preservative in vaccines. Recent studies identified the neurotoxic…”
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