Search Results - "Ángel Sánchez-Lamar"
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Antioxidant, photoprotective and antimutagenic properties of Phyllanthus spp. from Cuban flora
Published in Journal of pharmacy & pharmacognosy research (01-07-2017)“…Context: Sunlight ultraviolet (UV) radiation constitutes a significant physical carcinogen in nature. It could induce direct and indirect DNA damage, which if…”
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DNA Damage Induced by Late Spring Sunlight in Antarctica
Published in Photochemistry and photobiology (01-11-2020)“…Sunlight ultraviolet (UV) radiation constitutes an important environmental genotoxic agent that organisms are exposed to, as it can damage DNA directly,…”
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Genoprotective Effect of Phyllanthus orbicularis Extract Against UVA, UVB, and Solar Radiation
Published in Photochemistry and photobiology (01-09-2018)“…One approach to protect the human skin against harmful effects of solar ultraviolet (UV) radiation was to use natural products as photoprotectors. In this…”
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Evaluation of Genotoxic and DNA Photo-Protective Activity of Bryothamnion triquetrum and Halimeda incrassata Seaweeds Extracts
Published in Cosmetics (Basel) (01-09-2017)“…The ultraviolet (UV) component of sunlight is high on the earth surface, especially at low latitudes, raising the risk of skin diseases, including cancer. The…”
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Genotoxicity of ultraviolet light and sunlight in the bacterium Caulobacter crescentus: Wavelength-dependence
Published in Mutation research. Genetic toxicology and environmental mutagenesis (01-02-2024)“…The ultraviolet (UV) component of sunlight can damage DNA. Although most solar UV is absorbed by the ozone layer, wavelengths > 300 nm (UVA and UVB bands) can…”
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Xanthium strumarium extract inhibits mammalian cell proliferation through mitotic spindle disruption mediated by xanthatin
Published in Journal of ethnopharmacology (24-12-2016)“…Xanthium strumarium L. is a member of the Asteraceae family popularly used with multiple therapeutic purposes. Whole extracts of this plant have shown…”
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Xanthatin and 8-epi-xanthatin as new potential colchicine binding site inhibitors: a computational study
Published in Journal of molecular modeling (01-02-2023)“…Context Phytocompounds xanthatin and 8- epi -xanthatin, obtained from Xanthium chinese Mill , showed antitumoral activity in vitro related to the microtubules…”
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Xanthium strumarium´s xanthatins induces mitotic arrest and apoptosis in CT26WT colon carcinoma cells
Published in Phytomedicine (Stuttgart) (01-04-2019)“…Colorectal cancer is one of the most common malignancies worldwide and is associated with high mortality rates. We previously reported that Xanthium strumarium…”
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Xanthium strumarium L. Extracts Produce DNA Damage Mediated by Cytotoxicity in In Vitro Assays but Does Not Induce Micronucleus in Mice
Published in BioMed research international (01-01-2014)“…Xanthium strumarium L. is a member of the Asteraceae commonly used in Cuba, mainly as diuretic. Some toxic properties of this plant have also been reported…”
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Microtubules destabilizing agents binding sites in tubulin
Published in Journal of molecular structure (05-07-2022)“…•Five microtubule destabilizing agents binding sites have been described in tubulin.•Pharmacophore models have been proposed for three of these sites.•The…”
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Natural Bioactive Compounds Acting against Oxidative Stress in Chronic, Degenerative, and Infectious Diseases
Published in Oxidative medicine and cellular longevity (01-01-2018)“…[...]T. Zheng et al. reported the effects of salidroside, a bioactive molecule extracted from Rhodiola rosea plant, on high-fat diet-induced nonalcoholic fatty…”
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Aqueous extract of Pinus caribaea inhibits the damage induced by ultraviolet radiations, in plasmid DNA
Published in Journal of pharmacy & pharmacognosy research (01-01-2017)“…Context: The incidence of solar ultraviolet radiation (UV) on Earth has increased due to diminish of the ozone layer. This enviromental agent is highly…”
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Insights into the Phytochemistry of the Cuban Endemic Medicinal Plant Phyllanthus orbicularis : Fideloside, a Novel Bioactive 8- C -glycosyl 2,3-Dihydroflavonol
Published in Molecules (Basel, Switzerland) (06-08-2019)“…(Phyllanthaceae) is an endemic evergreen tropical plant of Cuba that grows in the western part of the island and is used in traditional medicine as an…”
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Utilización de la línea celular CHO en los ensayos de genotoxicidad
Published in Revista cubana de investigaciones biomédicas (01-04-1999)Get full text
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Antioxidant, photoprotective and antimutagenic properties of Phyllanthus spp. from Cuban flora
Published in Journal of pharmacy & pharmacognosy research (01-01-2017)“…Context: Sunlight ultraviolet (UV) radiation constitutes a significant physical carcinogen in nature. It could induce direct and indirect DNA damage, which if…”
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Toxic Evaluation of Cymbopogon citratus Chemical Fractions in E. coli
Published in Cosmetics (Basel) (01-06-2017)“…Cymbopogon citratus (DC) Stapf is consumed as a popular decoction owing to its nice flavor and hypotensor property. Its aqueous extract radioprotector and…”
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Genoprotection by complexation: The case of Phyllanthus orbicularis K extract
Published in Computational and theoretical chemistry (15-09-2019)“…[Display omitted] •Phyllanthus orbicularis K’s extract has anti-mutagenic effects the mechanism of which is elucidated.•Mutagenic amines are shown to be…”
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Antimutagenic mechanisms of Phyllanthus orbicularis when hydrogen peroxide is tested using Salmonella assay
Published in Mutation research (27-05-2002)“…Phyllanthus orbicularis is a medicinal plant, endemic to Cuba, whose aqueous extract has proven antiviral properties and antimutagenic activities against…”
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Modulation of rat and human cytochromes P450 involved in PhIP and 4-ABP activation by an aqueous extract of Phyllanthus orbicularis
Published in Journal of ethnopharmacology (01-02-2004)“…Phyllanthus orbicularis HBK (Euphorbiaceae) is a medicinal plant, endemic to Cuba, whose aqueous extract has proven antimutagenic effects against hydrogen…”
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