Search Results - "Álvaro Sánchez-Ferrer"

Neutrophils mediate Salmonella Typhimurium clearance through the GBP4 inflammasome-dependent production of prostaglandins by Tyrkalska, Sylwia D., Candel, Sergio, Angosto, Diego, Gómez-Abellán, Victoria, Martín-Sánchez, Fátima, García-Moreno, Diana, Zapata-Pérez, Rubén, Sánchez-Ferrer, Álvaro, Sepulcre, María P., Pelegrín, Pablo, Mulero, Victoriano

“…Inflammasomes are cytosolic molecular platforms that alert the immune system about the presence of infection. Here we report that zebrafish guanylate-binding…”
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Reduced nicotinamide mononucleotide is a new and potent NAD+ precursor in mammalian cells and mice by Zapata‐Pérez, Rubén, Tammaro, Alessandra, Schomakers, Bauke V., Scantlebery, Angelique M. L., Denis, Simone, Elfrink, Hyung L., Giroud‐Gerbetant, Judith, Cantó, Carles, López‐Leonardo, Carmen, McIntyre, Rebecca L., van Weeghel, Michel, Sánchez‐Ferrer, Álvaro, Houtkooper, Riekelt H.

“…Nicotinamide adenine dinucleotide (NAD+) homeostasis is constantly compromised due to degradation by NAD+‐dependent enzymes. NAD+ replenishment by…”
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A predictive model for hospitalization and survival to COVID-19 in a retrospective population-based study by Cisterna-García, Alejandro, Guillén-Teruel, Antonio, Caracena, Marcos, Pérez, Enrique, Jiménez, Fernando, Francisco-Verdú, Francisco J., Reina, Gabriel, González-Billalabeitia, Enrique, Palma, José, Sánchez-Ferrer, Álvaro, Botía, Juan A.

“…The development of tools that provide early triage of COVID-19 patients with minimal use of diagnostic tests, based on easily accessible data, can be of vital…”
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An uncharacterized FMAG_01619 protein from Fusobacterium mortiferum ATCC 9817 demonstrates that some bacterial macrodomains can also act as poly-ADP-ribosylhydrolases by García-Saura, Antonio Ginés, Zapata-Pérez, Rubén, Hidalgo, José Francisco, Cabanes, Juana, Gil-Ortiz, Fernando, Sánchez-Ferrer, Álvaro

“…Macrodomains constitute a conserved fold widely distributed that is not only able to bind ADP-ribose in its free and protein-linked forms but also can catalyse…”
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Molecular Characterization of a Novel N-Acetylneuraminate Lyase from Lactobacillus plantarum WCFS1 by Guiomar Sánchez-Carrón, María Inmaculada García-García, Ana Belén López-Rodríguez, Sofía Jiménez-García, Agustín Sola-Carvajal, Francisco García-Carmona, Álvaro Sánchez-Ferrer

“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Characterization and mutational analysis of a nicotinamide mononucleotide deamidase from Agrobacterium tumefaciens showing high thermal stability and catalytic efficiency by Martínez-Moñino, Ana Belén, Zapata-Pérez, Rubén, García-Saura, Antonio Ginés, Gil-Ortiz, Fernando, Pérez-Gilabert, Manuela, Sánchez-Ferrer, Álvaro

“…NAD+ has emerged as a crucial element in both bioenergetic and signaling pathways since it acts as a key regulator of cellular and organismal homeostasis…”
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Immunometabolic involvement of hepcidin genes in iron homeostasis, storage, and regulation in gilthead seabream (Sparus aurata) by Serna-Duque, Jhon A., Espinosa Ruiz, Cristóbal, Martínez Lopez, Salvadora, Sánchez-Ferrer, Álvaro, Esteban, Maria Ángeles

“…Iron is essential for all living things, especially marine organisms, due to its low availability in the marine environment. Iron regulation is key in all…”
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Biochemical characterization of a new nicotinamidase from an unclassified bacterium thriving in a geothermal water stream microbial mat community by Zapata-Pérez, Rubén, Martínez-Moñino, Ana-Belén, García-Saura, Antonio-Ginés, Cabanes, Juana, Takami, Hideto, Sánchez-Ferrer, Álvaro

“…Nicotinamidases are amidohydrolases that convert nicotinamide into nicotinic acid, contributing to NAD+ homeostasis in most organisms. In order to increase the…”
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Overexpression, Purification, and Biochemical Characterization of the Esterase Est0796 from Lactobacillus plantarum WCFS1 by Inmaculada, Navarro-González, Álvaro, Sánchez-Ferrer, Francisco, García-Carmona

“…Lactobacillus plantarum is a lactic acid bacterium that is encountered in an extensive range of foods such as fermented dairy products, meat, vegetables, and…”
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Combined Whole-Cell High-Throughput Functional Screening for Identification of New Nicotinamidases/Pyrazinamidases in Metagenomic/Polygenomic Libraries by Zapata-Pérez, Rubén, García-Saura, Antonio G, Jebbar, Mohamed, Golyshin, Peter N, Sánchez-Ferrer, Álvaro

“…Nicotinamidases catalyze the hydrolysis of the amide bond in nicotinamide (NAM) to produce ammonia and nicotinic acid (NA). These enzymes are an essential…”
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Characterization of a Novel N-Acetylneuraminate Lyase from Staphylococcus carnosus TM300 and Its Application to N-Acetylneuraminic Acid Production by García García, María Inmaculada, Sola Carvajal, Agustín, García Carmona, Francisco, Sánchez Ferrer, Álvaro

“…The possibility of incorporating N-acetylneuraminic acid (Neu5Ac) in infant formulas and other functional foods has opened up the need to synthesize…”
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New Insights into the Phylogeny and Gene Context Analysis of Binder of Sperm Proteins (BSPs) by Serrano, Edith, Martínez, Ana B, Arruga, Diana, Pérez-Pé, Rosaura, Sánchez-Ferrer, Álvaro, Muiño-Blanco, Teresa, Cebrián-Pérez, José A

“…Seminal plasma (SP) proteins support the survival of spermatozoa acting not only at the plasma membrane but also by inhibition of capacitation, resulting in…”
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Structural and functional analysis of Oceanobacillus iheyensis macrodomain reveals a network of waters involved in substrate binding and catalysis by Zapata-Pérez, Rubén, Gil-Ortiz, Fernando, Martínez-Moñino, Ana Belén, García-Saura, Antonio Ginés, Juanhuix, Jordi, Sánchez-Ferrer, Álvaro

“…Macrodomains are ubiquitous conserved domains that bind or transform ADP-ribose (ADPr) metabolites. In humans, they are involved in transcription, X-chromosome…”
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Molecular Characterization of a Novel Arylesterase from the Wine-Associated Acetic Acid Bacterium Gluconobacter oxidans 621H by Navarro-González, Inmaculada, Sánchez-Ferrer, Álvaro, García-Carmona, Francisco

“…An arylesterase from the wine-making acetic acid bacterium, Gluconobacter oxidans, was cloned and expressed into Escherichia coli. The soluble 76.8 kDa dimeric…”
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Insights into the evolution of sorbitol metabolism: phylogenetic analysis of SDR196C family by Sola Carvajal, Agustin, Garcia, Maria Inmaculada Garcia, Carmona, Francisco Garcia, Ferrer, Alvaro Sanchez

“…Short chain dehydrogenases/reductases (SDR) are NAD(P)(H)-dependent oxidoreductases with a highly conserved 3D structure and of an early origin, which has…”
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New insights into the phylogeny and molecular classification of nicotinamide mononucleotide deamidases by Sánchez-Carrón, Guiomar, Martínez-Moñino, Ana Belén, Sola-Carvajal, Agustín, Takami, Hideto, García-Carmona, Francisco, Sánchez-Ferrer, Álvaro

“…Nicotinamide mononucleotide (NMN) deamidase is one of the key enzymes of the bacterial pyridine nucleotide cycle (PNC). It catalyzes the conversion of NMN to…”
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Identification of a Novel β-Defensin Gene in Gilthead Seabream (Sparus aurata) by Ferez-Puche, M., Serna-Duque, Jhon A., Cuesta, Alberto, Sánchez-Ferrer, Álvaro, Esteban, María Ángeles

“…The excessive use of antibiotics in aquaculture favors the natural selection of multidrug-resistant bacteria, and antimicrobial peptides (AMPs) could be a…”
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Two duplicated piscidin genes from gilthead seabream (Sparus aurata) with different roles in vitro and in vivo by Serna-Duque, Jhon A., Cuesta, Alberto, Sánchez-Ferrer, Álvaro, Esteban, M. Ángeles

“…From the discovery of pleurocidin in skin mucus of winter flounder, many new related sequences have been found, forming a fish-exclusive family of…”
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Zebrafish models of COVID-19 by Tyrkalska, Sylwia D, Candel, Sergio, Pedoto, Annamaria, García-Moreno, Diana, Alcaraz-Pérez, Francisca, Sánchez-Ferrer, Álvaro, Cayuela, María L, Mulero, Victoriano

“…Abstract Although COVID-19 has only recently appeared, research studies have already developed and implemented many animal models for deciphering the secrets…”
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A ribonuclease III involved in virulence of Mucorales fungi has evolved to cut exclusively single-stranded RNA by Cánovas-Márquez, José Tomás, Falk, Sebastian, Nicolás, Francisco E, Padmanabhan, Subramanian, Zapata-Pérez, Rubén, Sánchez-Ferrer, Álvaro, Navarro, Eusebio, Garre, Victoriano

“…Abstract Members of the ribonuclease III (RNase III) family regulate gene expression by processing double-stranded RNA (dsRNA). This family includes eukaryotic…”
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