Search Results - "Álvarez‐Bernad, Beatriz"

Maytansinol Functionalization: Towards Useful Probes for Studying Microtubule Dynamics by Boiarska, Zlata, Pérez‐Peña, Helena, Abel, Anne‐Catherine, Marzullo, Paola, Álvarez‐Bernad, Beatriz, Bonato, Francesca, Santini, Benedetta, Horvath, Dragos, Lucena‐Agell, Daniel, Vasile, Francesca, Sironi, Maurizio, Díaz, J. Fernando, Prota, Andrea E., Pieraccini, Stefano, Passarella, Daniele

“…Maytansinoids are a successful class of natural and semisynthetic tubulin binders, known for their potent cytotoxic activity. Their wider application as…”
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Maytansinol Functionalization: Towards Useful Probes for Studying Microtubule Dynamics by Boiarska, Zlata, Pérez‐Peña, Helena, Abel, Anne‐Catherine, Marzullo, Paola, Álvarez‐Bernad, Beatriz, Bonato, Francesca, Santini, Benedetta, Horvath, Dragos, Lucena‐Agell, Daniel, Vasile, Francesca, Sironi, Maurizio, Díaz, J. Fernando, Prota, Andrea E., Pieraccini, Stefano, Passarella, Daniele

“…Invited for the cover of this issue are the groups of Professors Passarella and Pieraccini at the University of Milan, in collaboration with some of the…”
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Maytansinol Derivatives: Side Reactions as a Chance for New Tubulin Binders by Marzullo, Paola, Boiarska, Zlata, Pérez‐Peña, Helena, Abel, Anne‐Catherine, Álvarez‐Bernad, Beatriz, Lucena‐Agell, Daniel, Vasile, Francesca, Sironi, Maurizio, Altmann, Karl‐Heinz, Prota, Andrea E., Díaz, J. Fernando, Pieraccini, Stefano, Passarella, Daniele

“…Maytansinol is a valuable precursor for the preparation of maytansine derivatives (known as maytansinoids). Inspired by the intriguing structure of the…”
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PM534, an Optimized Target-Protein Interaction Strategy through the Colchicine Site of Tubulin by Lucena-Agell, Daniel, Guillén, María José, Matesanz, Ruth, Álvarez-Bernad, Beatriz, Hortigüela, Rafael, Avilés, Pablo, Martínez-Díez, Marta, Santamaría-Núñez, Gema, Contreras, Julia, Plaza-Menacho, Iván, Giménez-Abián, Juan F., Oliva, María A., Cuevas, Carmen, Díaz, J. Fernando

“…Targeting microtubules is the most effective wide-spectrum pharmacological strategy in antitumoral chemotherapy, and current research focuses on reducing main…”
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Effect of Clinically Used Microtubule Targeting Drugs on Viral Infection and Transport Function by Oliva, María Ángela, Tosat-Bitrián, Carlota, Barrado-Gil, Lucía, Bonato, Francesca, Galindo, Inmaculada, Garaigorta, Urtzi, Álvarez-Bernad, Beatriz, París-Ogáyar, Rebeca, Lucena-Agell, Daniel, Giménez-Abián, Juan Francisco, García-Dorival, Isabel, Urquiza, Jesús, Gastaminza, Pablo, Díaz, José Fernando, Palomo, Valle, Alonso, Covadonga

“…Microtubule targeting agents (MTAs) have been exploited mainly as anti-cancer drugs because of their impact on cellular division and angiogenesis…”
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Front Cover: Maytansinol Functionalization: Towards Useful Probes for Studying Microtubule Dynamics (Chem. Eur. J. 5/2023) by Boiarska, Zlata, Pérez‐Peña, Helena, Abel, Anne‐Catherine, Marzullo, Paola, Álvarez‐Bernad, Beatriz, Bonato, Francesca, Santini, Benedetta, Horvath, Dragos, Lucena‐Agell, Daniel, Vasile, Francesca, Sironi, Maurizio, Díaz, J. Fernando, Prota, Andrea E., Pieraccini, Stefano, Passarella, Daniele

“…Work with the elements of nature: Our building block, maytansinol, represented as a constellation of stars, is the main protagonist of the story. A ray of…”
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Cover Feature: Maytansinol Derivatives: Side Reactions as a Chance for New Tubulin Binders (Chem. Eur. J. 2/2022) by Marzullo, Paola, Boiarska, Zlata, Pérez‐Peña, Helena, Abel, Anne‐Catherine, Álvarez‐Bernad, Beatriz, Lucena‐Agell, Daniel, Vasile, Francesca, Sironi, Maurizio, Altmann, Karl‐Heinz, Prota, Andrea E., Díaz, J. Fernando, Pieraccini, Stefano, Passarella, Daniele

“…The interdisciplinary character of the Horizon2020‐MSCA‐EJD TubInTrain project allowed a challenging study of the peculiarity of maytansinoids as tubulin…”
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Chemical modulation of microtubule structure through the laulimalide/peloruside site by Estévez-Gallego, Juan, Álvarez-Bernad, Beatriz, Pera, Benet, Wullschleger, Christoph, Raes, Olivier, Menche, Dirk, Martínez, Juan Carlos, Lucena-Agell, Daniel, Prota, Andrea E., Bonato, Francesca, Bargsten, Katja, Cornelus, Jelle, Giménez-Abián, Juan Francisco, Northcote, Peter, Steinmetz, Michel O., Kamimura, Shinji, Altmann, Karl-Heinz, Paterson, Ian, Gago, Federico, Van der Eycken, Johan, Díaz, J. Fernando, Oliva, María Ángela

“…Taxanes are microtubule-stabilizing agents used in the treatment of many solid tumors, but they often involve side effects affecting the peripheral nervous…”
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Abstract 6239: PM534 is a novel microtubule-destabilizing agent with high affinity and potent antineoplastic properties by Oliva, Maria Ángela, Álvarez-Bernad, Beatriz, Lucena-Agell, Daniel, Diez, Marta Martínez, Guillén, María José, Nuñez, Gema Santamaría, Muñoz-Alonso, María José, Garrido-Martin, Eva M., Avilés, Pablo, Cuevas, Carmen, Díaz, J. Fernando

“…Abstract Background: Microtubule targeting compounds are a successful class of anticancer agents in the clinic. Although highly potent, the currently approved…”
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