Search Results - "(Curly) Morris, T. C. M."
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Evolution or revolution in multiple myeloma therapy and the role of the UK
Published in British journal of haematology (01-11-2020)“…Summary The knowledge of disease biology as well as the therapeutic landscape in multiple myeloma (MM) has expanded exponentially in recent years. These…”
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IgD multiple myeloma: biology, diagnosis, and treatment
Published in Leukemia & lymphoma (06-12-2022)“…IgD multiple myeloma is uncommon. Patients generally present at a younger age and have shorter progression free and overall survivals (OSs). Its rarity has…”
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ABCB1 (MDR1) rs1045642 is associated with increased overall survival in plasma cell myeloma
Published in Leukemia & lymphoma (01-01-2009)“…Multi-drug resistance (MDR) may compromise the successful management of haematological malignancies, impairing the effectiveness of chemotherapy. The…”
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4
Mutated IgHV1-69 gene usage represents a distinct subgroup associated with indolent disease in chronic lymphocytic leukemia
Published in Leukemia & lymphoma (01-04-2008)“…Biased IgHV gene usage in chronic lymphocytic leukemia (CLL) is well documented and suggests antigen involvement in leukemogenesis. IgHV1-69 is one of the most…”
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V(H)3-48 and V(H)3-53, as well as V(H)3-21, gene rearrangements define unique subgroups in CLL and are associated with biased lambda light chain restriction, homologous LCDR3 sequences and poor prognosis
Published in Leukemia research (01-02-2007)“…This study determined IgV(H) gene usage in 228 chronic lymphocytic leukaemia patients to investigate associations between gene usage and other biological or…”
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Stem Cell Harvesting after Bortezomib-Based Reinduction for Myeloma Relapsing after Autologous Transplantation: Results from the British Society of Blood and Marrow Transplantation/United Kingdom Myeloma Forum Myeloma X (Intensive) Trial
Published in Biology of blood and marrow transplantation (01-06-2016)“…Abstract The phase III British Society of Blood and Marrow Transplantation/United Kingdom Myeloma Forum Myeloma X trial (MMX) demonstrated prospectively, for…”
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Telomeric IGH Losses Detectable by Fluorescence in Situ Hybridization in Chronic Lymphocytic Leukemia Reflect Somatic V H Recombination Events
Published in The Journal of molecular diagnostics : JMD (2007)“…Routine interphase fluorescence in situ hybridization (FISH) analysis of chronic lymphocytic leukemia (CLL) with LSI IGH/CCND1 assay, applied to differentiate…”
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Telomeric IGH Losses Detectable by Fluorescence in Situ Hybridization in Chronic Lymphocytic Leukemia Reflect Somatic VH Recombination Events
Published in The Journal of molecular diagnostics : JMD (01-02-2007)“…Routine interphase fluorescence in situ hybridization (FISH) analysis of chronic lymphocytic leukemia (CLL) with LSI IGH/CCND1 assay, applied to differentiate…”
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9
Routine Analysis of IgVH Mutational Status in CLL Patients using BIOMED-2 Standardized Primers and Protocols
Published in Leukemia & lymphoma (01-09-2004)“…Current methods for the detection of IgVH mutational status in chronic lymphocytic leukemia (CLL), which identifies 2 subgroups of patients with significantly…”
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MDR-1, but not MDR-3 gene expression, is associated with unmutated IgVH genes and poor prognosis chromosomal aberrations in chronic lymphocytic leukemia
Published in Leukemia & lymphoma (01-11-2006)“…Two P-glycoprotein (P-gp) genes, MDR-1 (ABCB1) and MDR-3 (ABCB4), have been identified in humans. This study was designed to investigate whether associations…”
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Improved Laboratory Diagnosis of Bacterial and Fungal Infections in Patients with Hematological Malignancies using PCR and Ribosomal RNA Sequence Analysis
Published in Leukemia & lymphoma (01-08-2004)“…During October 1999 to November 2000, 98 blood culture specimens from the same number of febrile episodes originating from 49 patients with hematological…”
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Detection of tumor-derived antigen receptor DNA by polymerase chain reaction in the serum of patients with B-cell chronic lymphocytic leukemia
Published in Haematologica (Roma) (01-07-2005)“…Tumor-derived DNA is detectable in the serum of patients. In this study, tumor derived and mononuculear cell DNA from 50 patients with B-cell chronic…”
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13
Aggressive Natural Killer Cell Leukemia/Lymphoma: Case Report, use of Telesynergy™ and Review of the Literature
Published in Leukemia & lymphoma (01-06-2004)“…Natural killer cell malignancies, although increasingly recognized, remain rare tumors within the USA and Europe. They are somewhat more common in Asia, and…”
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